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Experimental Study of the Efficiency of Oxidized Dextran for Prevention of Influenza A/H5N1

tetano

Editor, Senior Moderator
Bull Exp Biol Med. 2014 Nov 19. [Epub ahead of print]
Experimental Study of the Efficiency of Oxidized Dextran for Prevention of Influenza A/H5N1.
Shkurupy VA1, Potapova OV, Sharkova TV, Troitskii AV, Gulyaeva EP, Bystrova TN, Shestopalov AM.
Author information
Abstract

Oxidized dextran is suggested for prevention of infection induced by influenza A/H5N1 viruses, methods of its use and doses are determined. Two intravenous injections of dextran 3 and 1 days before experimental infection of outbred mice by influenza A/H5N1 A/goose/ Krasnoozerskoye/627/05 virus resulted in a high preventive dose-dependent effect: the mean lifespan was 25% prolonged, the mortality decreased 3-fold.

PMID:
25403410
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25403410
 
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