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Expanding severe acute respiratory infection (SARI) surveillance beyond influenza: The process and data from 1 year of implementation in Vietnam

tetano

Editor, Senior Moderator
Influenza Other Respir Viruses. 2018 May 13. doi: 10.1111/irv.12571. [Epub ahead of print]
[h=1]Expanding severe acute respiratory infection (SARI) surveillance beyond influenza: The process and data from 1 year of implementation in Vietnam.[/h] Alroy KA[SUP]1[/SUP], Do TT[SUP]2[/SUP], Tran PD[SUP]3[/SUP], Dang TQ[SUP]3[/SUP], Vu LN[SUP]3[/SUP], Le NTH[SUP]3[/SUP], Dang AD[SUP]4[/SUP], Ngu ND[SUP]4[/SUP], Ngo TH[SUP]4[/SUP], Hoang PMV[SUP]4[/SUP], Phan LT[SUP]5[/SUP], Nguyen TV[SUP]5[/SUP], Nguyen LT[SUP]5[/SUP], Nguyen TV[SUP]5[/SUP], Vien MQ[SUP]6[/SUP], Le HX[SUP]6[/SUP], Dao AT[SUP]6[/SUP], Nguyen TB[SUP]6[/SUP], Pham DT[SUP]7[/SUP], Nguyen VTT[SUP]7[/SUP], Pham TN[SUP]7[/SUP], Phan BH[SUP]7[/SUP], Whitaker B[SUP]1[/SUP], Do TTT[SUP]2[/SUP], Dao PA[SUP]2[/SUP], Balajee SA[SUP]1[/SUP], Mounts AW[SUP]2,[/SUP][SUP]8[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] In 2016, as a component of the Global Health Security Agenda, the Vietnam Ministry of Health expanded its existing influenza sentinel surveillance for severe acute respiratory infections (SARI) to include testing for 7 additional viral respiratory pathogens. This article describes the steps taken to implement expanded SARI surveillance in Vietnam and reports data from 1 year of expanded surveillance.
[h=4]METHOD:[/h] The process of expanding the suite of pathogens for routine testing by real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) included laboratory trainings, procurement/distribution of reagents, and strengthening and aligning SARI surveillance epidemiology practices at sentinel sites and regional institutes (RI).
[h=4]RESULTS:[/h] Surveillance data showed that of 4,003 specimens tested by the RI laboratories, 20.2% (n = 810) were positive for influenza virus. Of the 3,193 influenza-negative specimens, 41.8% (n = 1,337) were positive for at least 1 non-influenza respiratory virus, of which 16.2% (n = 518), 13.4% (n = 428), and 9.6% (n = 308) tested positive for respiratory syncytial virus, rhinovirus, and adenovirus, respectively.
[h=4]CONCLUSIONS:[/h] The Government of Vietnam has demonstrated that expanding respiratory viral surveillance by strengthening and building upon an influenza platform is feasible, efficient, and practical. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.


[h=4]KEYWORDS:[/h] Vietnam; adenovirus; global health security; influenza virus; respiratory syncytial virus; rhinovirus; severe acute respiratory infection (SARI)

PMID: 29754431 DOI: 10.1111/irv.12571
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