tetano
Editor, Senior Moderator
Exp Ther Med
. 2022 May 23;24(1):462.
doi: 10.3892/etm.2022.11389. eCollection 2022 Jul.
Possible association between Guillain-Barré syndrome and SARS-CoV-2 infection in children: A case report and literature review
Ilaria Mussinatto[SUP] 1 [/SUP], Chiara Benevenuta[SUP] 1 [/SUP], Anna Caci[SUP] 1 [/SUP], Mario M Calvo[SUP] 1 [/SUP], Maria Impastato[SUP] 2 [/SUP], Massimo Barra[SUP] 3 [/SUP], Egidio Genovese[SUP] 4 [/SUP], Fabio Timeus[SUP] 1 [/SUP]
Affiliations
Abstract
Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in adults and in children, varying from mild to more debilitant symptoms, including fatigue, headache and dizziness. A series of studies have revealed a possible association between Guillain-Barré syndrome (GBS), the most common cause of acute flaccid paralysis at all ages, and SARS-CoV-2 infection. Case reports of novel coronavirus disease 2019 (COVID-19)-associated GBS mainly include adult patients, while only a few pediatric cases have been reported. The present study describes a case of GBS in an Italian 9-year-old girl with previous SARS-CoV-2 infection as a possible trigger, and also conducts a literature review on pediatric COVID-19-associated GBS cases.
Keywords: Guillain-Barré syndrome; children; coronavirus disease 2019; intravenous immunoglobulin.
. 2022 May 23;24(1):462.
doi: 10.3892/etm.2022.11389. eCollection 2022 Jul.
Possible association between Guillain-Barré syndrome and SARS-CoV-2 infection in children: A case report and literature review
Ilaria Mussinatto[SUP] 1 [/SUP], Chiara Benevenuta[SUP] 1 [/SUP], Anna Caci[SUP] 1 [/SUP], Mario M Calvo[SUP] 1 [/SUP], Maria Impastato[SUP] 2 [/SUP], Massimo Barra[SUP] 3 [/SUP], Egidio Genovese[SUP] 4 [/SUP], Fabio Timeus[SUP] 1 [/SUP]
Affiliations
- PMID: 35747147
- PMCID: PMC9204538
- DOI: 10.3892/etm.2022.11389
Abstract
Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in adults and in children, varying from mild to more debilitant symptoms, including fatigue, headache and dizziness. A series of studies have revealed a possible association between Guillain-Barré syndrome (GBS), the most common cause of acute flaccid paralysis at all ages, and SARS-CoV-2 infection. Case reports of novel coronavirus disease 2019 (COVID-19)-associated GBS mainly include adult patients, while only a few pediatric cases have been reported. The present study describes a case of GBS in an Italian 9-year-old girl with previous SARS-CoV-2 infection as a possible trigger, and also conducts a literature review on pediatric COVID-19-associated GBS cases.
Keywords: Guillain-Barré syndrome; children; coronavirus disease 2019; intravenous immunoglobulin.