tetano
Editor, Senior Moderator
J Vet Med Sci. 2017 Apr 10. doi: 10.1292/jvms.16-0603. [Epub ahead of print]
[h=1]Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses.[/h] Nakashima R[SUP]1[/SUP], Kawamoto M, Miyazaki S, Onishi R, Furusaki K, Osaki M, Kirisawa R, Sakudo A, Onodera T.
[h=3]Author information[/h]
[h=3]Abstract[/h] In this study, the virucidal effect of a novel electrically charged disinfectant CAC-717 was investigated. CAC-717 is produced by applying an electric field to mineral water containing calcium hydrogen carbonate to generate mesoscopic crystals. Virus titration analysis showed a >3 log reduction of influenza A viruses after treatment with CAC-717 for 1 min in room temperature, while infectivity was undetectable after 15 min treatment. Adding bovine serum albumin to CAC-717 solution did not affect the disinfectant effect. Although CAC-717 is an alkaline solution (pH=12.39), upon contact with human tissue, its pH becomes almost physiological (pH 8.84) after accelerated electric discharge, which enables its use against influenza viruses. Therefore, CAC-717 may be used as a preventative measure against influenza A viruses and for biosecurity in the environment.
PMID: 28392537 DOI: 10.1292/jvms.16-0603
[h=1]Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses.[/h] Nakashima R[SUP]1[/SUP], Kawamoto M, Miyazaki S, Onishi R, Furusaki K, Osaki M, Kirisawa R, Sakudo A, Onodera T.
[h=3]Author information[/h]
[h=3]Abstract[/h] In this study, the virucidal effect of a novel electrically charged disinfectant CAC-717 was investigated. CAC-717 is produced by applying an electric field to mineral water containing calcium hydrogen carbonate to generate mesoscopic crystals. Virus titration analysis showed a >3 log reduction of influenza A viruses after treatment with CAC-717 for 1 min in room temperature, while infectivity was undetectable after 15 min treatment. Adding bovine serum albumin to CAC-717 solution did not affect the disinfectant effect. Although CAC-717 is an alkaline solution (pH=12.39), upon contact with human tissue, its pH becomes almost physiological (pH 8.84) after accelerated electric discharge, which enables its use against influenza viruses. Therefore, CAC-717 may be used as a preventative measure against influenza A viruses and for biosecurity in the environment.
PMID: 28392537 DOI: 10.1292/jvms.16-0603