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Eurosurveillance: Phylogenetic analysis of highly pathogenic avian influenza A(H5N8) virus outbreak strains provides evidence for four separate intro

tetano

Editor, Senior Moderator
Eurosurveillance, Volume 20, Issue 26, 02 July 2015
Surveillance and outbreak reports
Phylogenetic analysis of highly pathogenic avian influenza A(H5N8) virus outbreak strains provides evidence for four separate introductions and one between-poultry farm transmission in the Netherlands, November 2014
R J Bouwstra[SUP]1[/SUP], G Koch[SUP]1[/SUP], R Heutink[SUP]1[/SUP], F Harders[SUP]1[/SUP], A van der Spek[SUP]2[/SUP], A R Elbers ()[SUP]1[/SUP], A Bossers[SUP]1[/SUP]
  • Central Veterinary Institute part of Wageningen UR, Lelystad, the Netherlands
  • Netherlands Food and Consumer and Product Safety Authority, Utrecht, the Netherlands

Citation style for this article: Bouwstra RJ, Koch G, Heutink R, Harders F, van der Spek A, Elbers AR, Bossers A. Phylogenetic analysis of highly pathogenic avian influenza A(H5N8) virus outbreak strains provides evidence for four separate introductions and one between-poultry farm transmission in the Netherlands, November 2014. Euro Surveill. 2015;20(26):pii=21174. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21174
Date of submission: 26 March 2015

[SIZE=+0]Phylogenetic analysis of highly pathogenic avian influenza A(H5N8) virus strains causing outbreaks in Dutch poultry farms in 2014 provides evidence for separate introduction of the virus in four outbreaks in farms located 16?112 km from each other and for between-farm transmission between the third and fourth outbreak in farms located 550 m from each other. In addition, the analysis showed that all European and two Japanese H5N8 virus strains are very closely related and seem to originate from a calculated common ancestor, which arose between July and September 2014. Our findings suggest that the Dutch outbreak virus strain ?Ter Aar? and the first German outbreak strain from 2014 shared a common ancestor. In addition, the data indicate that the Dutch outbreak viruses descended from an H5N8 virus that circulated around 2009 in Asia, possibly China, and subsequently spread to South Korea and Japan and finally also to Europe. Evolution of the virus seemed to follow a parallel track in Japan and Europe, which supports the hypothesis that H5N8 virus was exchanged between migratory wild waterfowl at their breeding grounds in Siberia and from there was carried by migrating waterfowl to Europe.

full article
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http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21174
 
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