tetano
Editor, Senior Moderator
Euro Surveill. 2015 Feb 26;20(8). pii: 21043.
[h=1]Trivalent inactivated seasonal influenza vaccine effectiveness for the prevention of laboratory-confirmed influenza in a Scottish population 2000 to 2009.[/h] Simpson C[SUP]1[/SUP], Lone N, Kavanagh K, Ritchie L, Robertson C, Sheikh A, McMenamin J.
[h=3]Author information[/h]
PMID: 25742433 [PubMed - in process]
[SIZE=+0]To evaluate seasonal trivalent inactivated influenza vaccine effectiveness (VE) in Scotland, we performed a Scotland-wide linkage of patient-level primary care, hospital and virological swab data from 3,323 swabs (pooling data over nine influenza seasons: 2000/01 to 2008/09). We estimated the VE for reducing real-time RT-PCR-confirmed influenza using a test-negative study design. Vaccination was associated with a 57% (95% confidence interval (CI): 31?73) reduction in the risk of PCR-confirmed influenza. VE was 60% (95% CI: 22?79) for patients younger than 65 years and clinically at risk of serious complications from influenza, and 19% (95% CI: −104 to 68) for any individual 65 years and older. Vaccination was associated with substantial, sustained reductions in laboratory-confirmed influenza in the general population and younger patients in clinical at-risk groups.[/SIZE]
http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21043
[h=1]Trivalent inactivated seasonal influenza vaccine effectiveness for the prevention of laboratory-confirmed influenza in a Scottish population 2000 to 2009.[/h] Simpson C[SUP]1[/SUP], Lone N, Kavanagh K, Ritchie L, Robertson C, Sheikh A, McMenamin J.
[h=3]Author information[/h]
PMID: 25742433 [PubMed - in process]
[SIZE=+0]To evaluate seasonal trivalent inactivated influenza vaccine effectiveness (VE) in Scotland, we performed a Scotland-wide linkage of patient-level primary care, hospital and virological swab data from 3,323 swabs (pooling data over nine influenza seasons: 2000/01 to 2008/09). We estimated the VE for reducing real-time RT-PCR-confirmed influenza using a test-negative study design. Vaccination was associated with a 57% (95% confidence interval (CI): 31?73) reduction in the risk of PCR-confirmed influenza. VE was 60% (95% CI: 22?79) for patients younger than 65 years and clinically at risk of serious complications from influenza, and 19% (95% CI: −104 to 68) for any individual 65 years and older. Vaccination was associated with substantial, sustained reductions in laboratory-confirmed influenza in the general population and younger patients in clinical at-risk groups.[/SIZE]
http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21043