Eurosurv. The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019

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[h=2]The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019

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• Deshan Yu[SUP]1,2[/SUP], Guofeng Xiang[SUP]1,3[/SUP], Wenfei Zhu[SUP]1,4[/SUP], Xia Lei[SUP]1,5[/SUP], Baodi Li[SUP]2[/SUP], Yao Meng[SUP]4[/SUP], Lei Yang[SUP]4[/SUP], Hongyan Jiao[SUP]6[/SUP], Xiyan Li[SUP]4[/SUP], Weijuan Huang[SUP]4[/SUP], Hejiang Wei[SUP]4[/SUP], Yanping Zhang[SUP]7[/SUP], Yan Hai[SUP]5[/SUP], Hui Zhang[SUP]2[/SUP], Hua Yue[SUP]5[/SUP], Shumei Zou[SUP]4[/SUP], Xiang Zhao[SUP]4[/SUP], Chao Li[SUP]7[/SUP], Deng Ao[SUP]6[/SUP], Ye Zhang[SUP]4[/SUP], Minju Tan[SUP]4[/SUP], Jia Liu[SUP]4[/SUP], Xuemei Zhang[SUP]6[/SUP], George F. Gao[SUP]4,7[/SUP], Lei Meng[SUP]2,8[/SUP], Dayan Wang[SUP]4,8[/SUP]

After no reported human cases of highly pathogenic avian influenza (HPAI) H7N9 for over a year, a case with severe disease occurred in late March 2019. Among HPAI H7N9 viral sequences, those recovered from the case and from environmental samples of a poultry slaughtering stall near their home formed a distinct clade from 2017 viral sequences. Several mutations possibly associated to antigenic drift occurred in the haemagglutinin gene, potentially warranting update of H7N9 vaccine strains.

full article

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2019.24.21.1900273#html_fulltext