Eurosurv. Risk of severe COVID-19 from the Delta and Omicron variants in relation to vaccination status, sex, age and comorbidities – surveillance res

[tetano]

• Fredrik Kahn[SUP]1[/SUP] , Carl Bonander[SUP]2[/SUP] , Mahnaz Moghaddassi[SUP]3[/SUP] , Magnus Rasmussen[SUP]1[/SUP] , Ulf Malmqvist[SUP]4[/SUP] , Malin Inghammar[SUP]1[/SUP] , Jonas Björk[SUP]4,5[/SUP]

We compared the risk of severe COVID-19 during two periods 2021 and 2022 when Delta and Omicron, respectively, were the dominating virus variants in Scania county, Sweden. We adjusted for differences in sex, age, comorbidities, prior infection and vaccination. Risk of severe disease from Omicron was markedly lower among vaccinated cases. It was also lower among the unvaccinated but remained high (> 5%) for older people and middle-aged men with two or more comorbidities. Efforts to increase vaccination uptake should continue.

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https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.9.2200121#html_fulltext