Eurosurv. Outbreak of autochthonous West Nile virus infection in Lazio region, Italy, July to August 2025: preliminary investigation

[tetano]

• Ilaria Mussetto[SUP]1,*[/SUP] , Andrea Bongiovanni[SUP]1,*[/SUP] , Francesca Colavita[SUP]1[/SUP] , Cristina Giambi[SUP]2[/SUP] , Marcello Giovanni Sala[SUP]3[/SUP] , Cosmo Del Borgo[SUP]4[/SUP] , Fabrizio Carletti[SUP]1[/SUP] , Maria Teresa Scicluna[SUP]3[/SUP] , Alessandro Zerbetto[SUP]2[/SUP] , Angela Corpolongo[SUP]1[/SUP] , Federico Romiti[SUP]3[/SUP] , Maria Beatrice Valli[SUP]1[/SUP] , Stefania Vaglio[SUP]5[/SUP] , Roberto Giammattei[SUP]6[/SUP] , Paola Scognamiglio[SUP]1,7[/SUP] , Gabriella De Carli[SUP]1[/SUP] , Alessandro Agresta[SUP]1[/SUP] , Claudio De Liberato[SUP]3[/SUP] , Giuseppe Di Luzio[SUP]8[/SUP] , Florindo Micarelli[SUP]2[/SUP] , Emanuele Nicastri[SUP]1[/SUP] , Andrea Siddu[SUP]7[/SUP] , Valeria Ficarelli[SUP]7[/SUP] , Enrico Girardi[SUP]1[/SUP] , Fabrizio Maggi[SUP]1[/SUP] , Francesco Vairo[SUP]1[/SUP] , the Lazio WNV Outbreak Group[SUP]9[/SUP]

In July–18 August 2025, 171 autochthonous cases with West Nile virus (WNV) infection were confirmed in Lazio, Italy: four asymptomatic blood donors, 110 with WNV fever, 57 with neuroinvasive syndrome and nine deaths. WNV lineage 2 was detected in two neuroinvasive cases. Infection with WNV was confirmed in 28 horses, five crows and a Culex pipiens pool. We present the preliminary epidemiological and phylogenetic analysis of the outbreak and the public health measures taken within a One Health approach.​

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.35.2500634#html_fulltext
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