Eurosurv. mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of nat

[tetano]

• Baltazar Nunes[SUP]1,2[/SUP] , Ana Paula Rodrigues[SUP]1[/SUP] , Irina Kislaya[SUP]1,2[/SUP] , Camila Cruz[SUP]3[/SUP] , André Peralta-Santos[SUP]4[/SUP] , João Lima[SUP]3[/SUP] , Pedro Pinto Leite [SUP]4[/SUP] , Duarte Sequeira[SUP]3[/SUP] , Carlos Matias Dias [SUP]1,2[/SUP] , Ausenda Machado[SUP]1,2[/SUP]

Through deterministic data linkage of health registries, mRNA vaccine effectiveness (VE) against COVID-19-related hospitalisations and deaths was measured in 1,880,351 older adults. VE against hospitalisations was 94% (95% confidence interval (CI): 88–97) and 82% (95% CI: 72–89) for those 65–79 and ≥ 80 years old, with no evidence of waning 98 days after dose two. VE against mortality was 96% (95% CI: 92–98) and 81% (95% CI: 74–87) in these two age groups.


full article

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.38.2100833