Eurosurv. Case series of the first five human infections with monkeypox virus clade Ib and report on the public health response, United Kingdom, Octob

[tetano]

• Muhammad Ibaad Alvi[SUP]1[/SUP] , Merav Kliner[SUP]1[/SUP] , William Welfare[SUP]1[/SUP] , N Claire Gordon[SUP]1[/SUP] , Sherine Thomas[SUP]1[/SUP] , Simon Padfield[SUP]1[/SUP] , Hannah E Emmett[SUP]1[/SUP] , Ellen Heinsbroek[SUP]1[/SUP] , Gareth J Hughes[SUP]1[/SUP] , Natalie Groves[SUP]1[/SUP] , Eileen Gallagher[SUP]1[/SUP] , Steven Pullan[SUP]1[/SUP] , Amy Belfield[SUP]1[/SUP] , Catherine F Houlihan[SUP]1,9,10[/SUP] , Tommy Rampling[SUP]1,9,10,11[/SUP] , Geraldine O’Hara[SUP]1,4[/SUP] , Anne Tunbridge[SUP]2[/SUP] , Jake Dunning[SUP]3[/SUP] , Elizabeth Whittaker[SUP]5[/SUP] , Alejandra Alonso[SUP]6[/SUP] , Mike Beadsworth[SUP]7[/SUP] , Brendan AI Payne[SUP]8[/SUP] , Meera Chand[SUP]1[/SUP] , Susan Hopkins[SUP]1[/SUP] , Gillian Armstrong[SUP]1[/SUP]

We report two importations of monkeypox virus clade Ib infection to the United Kingdom in 2024. The first was a traveller returning from Tanzania, Rwanda and Uganda, the second from Uganda. Both presented with fever and typical skin lesions; 147 contacts were followed up, 19 vaccinated with MVA-BN. Three household contacts of the first individual, including two children, became infected. These are the first reported autochthonous transmissions of clade Ib in Europe, and first paediatric cases outside the African continent.
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https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.10.2500131