Eurosurv. A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22

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• Hanne-Dorthe Emborg[SUP]1[/SUP] , Lasse S Vestergaard[SUP]1[/SUP] , Amanda Bolt Botnen[SUP]1[/SUP] , Jens Nielsen[SUP]1[/SUP] , Tyra G Krause[SUP]1[/SUP] , Ramona Trebbien

We estimated interim influenza A vaccine effectiveness (VE) following a late sharp rise in cases during an influenza A(H3N2)-dominated 2021/22 season, after lifting COVID-19 restrictions. In children aged 2–6 years offered a live attenuated influenza vaccine, adjusted VE was 62.7% (95% CI: 10.9–84.4) in hospitalised and 64.2% (95% CI: 50.5–74.1) in non-hospitalised children. In non-hospitalised patients aged 7–44 years, VE was 24.8% (95% CI: 12.8–35.2); VE was non-significant in remaining age groups and hospital/non-hospital settings.



full article

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.15.2200278