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Euroasian J Hepatogastroenterol . Clinical Manifestations of Hospitalized COVID-19 Patients in Bangladesh: A 14-day Observational Study

tetano

Editor, Senior Moderator
Euroasian J Hepatogastroenterol


. Jan-Jun 2021;11(1):14-20.
doi: 10.5005/jp-journals-10018-1340.
Clinical Manifestations of Hospitalized COVID-19 Patients in Bangladesh: A 14-day Observational Study


Modhusudon Shaha[SUP] 1 2 [/SUP], Md A Islam[SUP] 3 [/SUP], Faizul Huq[SUP] 4 [/SUP], Bithi Roy[SUP] 5 [/SUP], Md A Kabir[SUP] 1 [/SUP], Md Salimullah[SUP] 2 [/SUP], Mamun Al Mahtab[SUP] 6 [/SUP], Sheikh Mf Akbar[SUP] 7 [/SUP]



Affiliations

Abstract

Objectives: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is currently a significant public health concern and causing a pandemic in the world. Despite immense attention to the coronavirus disease 2019 (COVID-19), very little attention has been given to the kinetics of disease progression in infected patients. Therefore, in this study, we present a 14-day clinical observation of hospital-admitted COVID-19 patients.
Methods: After recording the demography of 42 COVID-19 patients on day 1, we observed the clinical progression for 14 days by investigating the hematological and biochemical responses of patients' blood and serum, respectively.
Results: Approximately, 62% of the hospital-admitted COVID-19 patients presented cough, followed by fever (∼52%). The top comorbidities of these patients were hypertension (30%) and diabetes mellitus (19%). The average blood hemoglobin (Hb) level was slightly low among the patients in the early days of infection and went up to the normal level on the later days. A substantial increase in the level of ALT or SGPT [up to 106 IU/L; standard error of the mean (SEM): 12.64] and AST or SGOT (up to 64.35 IU/L; SEM: 5.013) in COVID-19 patients was observed, which may suggest that infection with coronavirus is associated with the functionality of other organs of COVID-19 patients.
Conclusion: This 14-day observational study may help clinicians to decide the choice of treatment for COVID-19 patients.
How to cite this article: Shaha M, Islam MA, Huq F, et al. Clinical Manifestations of Hospitalized COVID-19 Patients in Bangladesh: A 14-day Observational Study. Euroasian J Hepato-Gastroenterol 2021;11(1):14-20.

Keywords: Blood hemoglobin; COVID-19; Clinical manifestations; Comorbidity; Liver functionality; Pneumonia.
 
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