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Euro Surveill. Micro-simulation of a smallpox outbreak using official register data

Giuseppe

Emeritus
Micro-simulation of a smallpox outbreak using official register data (Euro Surveill., abstract, edited)


[Source: Eurosurveillance.org, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19651">Eurosurveillance - View Article</cite>. Abstract, edited.]

Eurosurveillance, Volume 15, Issue 35, 02 September 2010

Research articles

Micro-simulation of a smallpox outbreak using official register data

L Brouwers 1,2, M Boman 2,3, M Camitz 1,4,5, K M?kil? 1, A Tegnell 6
1. Swedish Institute for Infectious Disease Control, Department of Epidemiology, Solna, Sweden
2. Royal Institute of Technology, KTH/ICT/SCS, Kista, Sweden
3. Swedish Institute of Computer Science (SICS), Kista, Sweden
4. Department for Biostatistics and Epidemiology, Karolinska Institute, Solna, Sweden
5. Department of Sociology, Stockholm University, Sweden
6. National Board of Health and Welfare, Stockholm, Sweden

Citation style for this article: Brouwers L, Boman M, Camitz M, M?kil? K, Tegnell A. Micro-simulation of a smallpox outbreak using official register data . Euro Surveill. 2010;15(35):pii=19651. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19651

Date of submission: 01 June 2009


To explore the efficacy of four vaccine-based policy strategies (ring vaccination, targeted vaccination, mass vaccination, and pre-vaccination of healthcare personnel combined with ring vaccination) for controlling smallpox outbreaks in Sweden, disease transmission on a spatially explicit social network was simulated. The mixing network was formed from high-coverage official register data of the entire Swedish population, building on the Swedish Total Population Register, the Swedish Employment Register, and the Geographic Database of Sweden. The largest reduction measured in the number of infections was achieved when combining ring vaccination with a pre-vaccination of healthcare personnel. In terms of per dose effectiveness, ring vaccination was by far the most effective strategy. The results can to some extent be adapted to other diseases and environments, including other countries, and the methods used can be analysed in their own right.

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