Giuseppe
Emeritus
[Source: Eurosurveillance, full page: (LINK). Abstract, edited.]
Eurosurveillance, Volume 18, Issue 41, 10 October 2013
Research articles
Late season interim estimates of influenza vaccine effectiveness reliably predict end of season estimates in Victoria, Australia, 2007 to 2012
S G Sullivan <SUP>1</SUP>, H Kelly<SUP>2</SUP><SUP>,3</SUP>
<SUP></SUP>
<SUP>1</SUP>WHO Collaborating Centre for Reference and Research on Influenza, Melbourne, Australia - 2 Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia - 3 Australian National University, Canberra, Australia
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Citation style for this article: Sullivan SG, Kelly H. Late season interim estimates of influenza vaccine effectiveness reliably predict end of season estimates in Victoria, Australia, 2007 to 2012 . Euro Surveill. 2013;18(41)
ii=20605. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20605
Date of submission: 24 September 2013
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Twice each year the World Health Organization makes a recommendation for the composition of the influenza vaccine, based on circulating strains of influenza A(H3N2), A(H1N1) and B. Strain selection has always been based on immunogenicity studies with limited human data. Immunogenicity can be considered as a proxy for vaccine effectiveness (VE). However, only interim VE estimates for the target hemisphere can be considered in time for the strain selection meeting. Using surveillance data from Victoria, Australia, we retrospectively estimated and compared interim and final VE estimates for 2007 to 2012. In general, interim estimates were within five percentage points of final estimates. However, estimates made too early or in years of low influenza activity may be unreliable.
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Eurosurveillance, Volume 18, Issue 41, 10 October 2013
Research articles
Late season interim estimates of influenza vaccine effectiveness reliably predict end of season estimates in Victoria, Australia, 2007 to 2012
S G Sullivan <SUP>1</SUP>, H Kelly<SUP>2</SUP><SUP>,3</SUP>
<SUP></SUP>
<SUP>1</SUP>WHO Collaborating Centre for Reference and Research on Influenza, Melbourne, Australia - 2 Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia - 3 Australian National University, Canberra, Australia
_____
Citation style for this article: Sullivan SG, Kelly H. Late season interim estimates of influenza vaccine effectiveness reliably predict end of season estimates in Victoria, Australia, 2007 to 2012 . Euro Surveill. 2013;18(41)
ii=20605. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20605 Date of submission: 24 September 2013
_____
Twice each year the World Health Organization makes a recommendation for the composition of the influenza vaccine, based on circulating strains of influenza A(H3N2), A(H1N1) and B. Strain selection has always been based on immunogenicity studies with limited human data. Immunogenicity can be considered as a proxy for vaccine effectiveness (VE). However, only interim VE estimates for the target hemisphere can be considered in time for the strain selection meeting. Using surveillance data from Victoria, Australia, we retrospectively estimated and compared interim and final VE estimates for 2007 to 2012. In general, interim estimates were within five percentage points of final estimates. However, estimates made too early or in years of low influenza activity may be unreliable.
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