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Euro Surveill. Emergence of carbapenemase-producing Enterobacteriaceae in France, 2004 to 2011

Giuseppe

Emeritus
[Source: Eurosurveillance, full text: (LINK). Abstract, edited.]


Eurosurveillance, Volume 16, Issue 22, 02 June 2011
Surveillance and outbreak reports

Emergence of carbapenemase-producing Enterobacteriaceae in France, 2004 to 2011



S Vaux<SUP>1</SUP>, A Carbonne<SUP>2</SUP>, J M Thiolet<SUP>1</SUP>, V Jarlier<SUP>3</SUP>, B Coignard ()<SUP>1</SUP>, RAISIN and Expert Laboratories Groups<SUP>4</SUP>
  1. French Institute for Public Health Surveillance (Institut de Veille Sanitaire, InVS), Saint-Maurice, France
  2. Centre de coordination de la lutte contre les infections nosocomiales (CClin) Nord, Paris, France
  3. Pierre et Marie Curie (Paris 6) University (EA1541), Paris, France
  4. The participants of these groups are listed at the end of the article
<HR>
Citation style for this article: Vaux S, Carbonne A, Thiolet JM, Jarlier V, Coignard B, RAISIN and Expert Laboratories Groups. Emergence of carbapenemase-producing Enterobacteriaceae in France, 2004 to 2011 . Euro Surveill. 2011;16(22):pii=19880. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19880
Date of submission: 17 December 2010
<HR>Emergence of carbapenemase-producing Enterobacteriaceae (CPE) is currently a major public health concern worldwide. This study showed that 53 episodes of CPE infection or colonisation have been notified by French healthcare facilities since 2004. A sharp increase in the number of notifications was observed in the last three years. Oxacillinase (OXA)-48 and Klebsiella pneumoniae carbapenemase (KPC) beta-lactamases were the most frequent enzymes reported in these episodes. The index cases in most episodes were patients with a history of hospitalisation abroad within the previous year. Around a third of the episodes (n=18) led to secondary transmission in hospitals but most of them were controlled due to reinforced measures. Reinforcement of screening and control measures at national level when there is cross-border transfer of patients, along with overall reinforcement of infection control and antimicrobial stewardship worldwide, is urgently needed to contain the spread of CPE.
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