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Euro Surveill. Community outbreak of group B meningococcal disease in southwest France ? December 2008 to September 2009

Giuseppe

Emeritus
Community outbreak of group B meningococcal disease in southwest France ? December 2008 to September 2009 (Euro Surveill., abstract, edited)


[Source: Eurosurveillance.org, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19665">Eurosurveillance - View Article</cite>. Abstract, edited.]

Eurosurveillance, Volume 15, Issue 37, 16 September 2010

Surveillance and outbreak reports

Community outbreak of group B meningococcal disease in southwest France ? December 2008 to September 2009

E Delisle 1,2, S Larrieu 1, J Sim?es 3, N Laylle 3, M De Pommerol 1, M K Taha 4, J L Termignon 5, I Parent du Ch?telet 6
1. Branch of the Institut de Veille Sanitaire in the R?gion Aquitaine (InVS, French Institute for Public Health Surveillance), Bordeaux, France
2. Programme de Formation ? l'Epid?miologie de Terrain (PROFET, French Training Program in Field Epidemiology), Institut de Veille Sanitaire (InVS, French Institute for Public Health Surveillance), Saint-Maurice, France
3. Health District Office, Mont-de-Marsan, France
4. National Reference Centre for Meningococci, Institut Pasteur, Paris, France
5. French Agency of Health, Ministry of Health, Paris, France
6. Department of Infectious Diseases, Institut de Veille Sanitaire (InVS, French Institute for Public Health Surveillance), Saint-Maurice, France

Citation style for this article: Delisle E, Larrieu S, Sim?es J, Laylle N, De Pommerol M, Taha MK, Termignon JL, Parent du Ch?telet I. Community outbreak of group B meningococcal disease in southwest France ? December 2008 to September 2009. Euro Surveill. 2010;15(37):pii=19665. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19665

Date of submission: 03 March 2010


Between December 2008 and September 2009, 11 cases of invasive meningococcal disease (IMD) group B were reported in a 20 km diameter area in the D?partement Landes, France. Two of them presented with purpura fulminans and one of them died. The strain responsible for this community outbreak was of the clonal complex ST-269.The incidence rate for IMD group B was 3 per 100,000 inhabitants in Landes from week 40 in 2008 to week 40 in 2009; it was the highest in France during that period. The number of cases observed was significantly higher than expected, especially in young adults (standardised incidence ratio: 23.5, p<0.001). A nightclub located in the 20 km diameter area was a possible place of transmission and a prophylaxis recommended for the staff members helped in decreasing the transmission. However, several cases notified later suggested that the bacteria circulated during several months through healthy carriers in the community. This situation prompted increased surveillance of IMD in Landes and medical practitioners were asked to remain vigilant because of the possible emergence of new cases within the following months.

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