Giuseppe
Emeritus
Ceftriaxone treatment failure of pharyngeal gonorrhoea verified by international recommendations, Sweden, July 2010 (Euro Surveill., abstract, edited)
[Source: Eurosurveillance, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19792">Eurosurveillance - View Article</cite>. Abstract, edited.]
Eurosurveillance, Volume 16, Issue 6, 10 February 2011
Rapid communications
Ceftriaxone treatment failure of pharyngeal gonorrhoea verified by international recommendations, Sweden, July 2010
M Unemo 1, D Golparian 1, A Hestner 2
1. Swedish Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Microbiology, ?rebro University Hospital, ?rebro, Sweden
2. Department of Dermatology and Venereology, K?rnsjukhuset, Sk?vde, Sweden
Citation style for this article: Unemo M, Golparian D, Hestner A. Ceftriaxone treatment failure of pharyngeal gonorrhoea verified by international recommendations, Sweden, July 2010. Euro Surveill. 2011;16(6)
ii=19792. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19792
Date of submission: 24 January 2011
This report describes one case of verified treatment failure of pharyngeal gonorrhoea using ceftriaxone in Sweden. Previous reports described verified treatment failure of urogenital gonorrhoea using the internationally recommended first-line drug cefixime, but not with ceftriaxone, the last remaining option for empirical treatment of gonorrhoea. Enhanced awareness of clinical failures, pharmacodynamic considerations, follow-up and test of cure, adherence to appropriate case management and treatment guidelines as well as verification/falsification of presumed clinical treatment failures should be emphasised worldwide.
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[Source: Eurosurveillance, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19792">Eurosurveillance - View Article</cite>. Abstract, edited.]
Eurosurveillance, Volume 16, Issue 6, 10 February 2011
Rapid communications
Ceftriaxone treatment failure of pharyngeal gonorrhoea verified by international recommendations, Sweden, July 2010
M Unemo 1, D Golparian 1, A Hestner 2
1. Swedish Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Microbiology, ?rebro University Hospital, ?rebro, Sweden
2. Department of Dermatology and Venereology, K?rnsjukhuset, Sk?vde, Sweden
Citation style for this article: Unemo M, Golparian D, Hestner A. Ceftriaxone treatment failure of pharyngeal gonorrhoea verified by international recommendations, Sweden, July 2010. Euro Surveill. 2011;16(6)
ii=19792. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19792Date of submission: 24 January 2011
This report describes one case of verified treatment failure of pharyngeal gonorrhoea using ceftriaxone in Sweden. Previous reports described verified treatment failure of urogenital gonorrhoea using the internationally recommended first-line drug cefixime, but not with ceftriaxone, the last remaining option for empirical treatment of gonorrhoea. Enhanced awareness of clinical failures, pharmacodynamic considerations, follow-up and test of cure, adherence to appropriate case management and treatment guidelines as well as verification/falsification of presumed clinical treatment failures should be emphasised worldwide.
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