tetano
Editor, Senior Moderator
Eur Rev Med Pharmacol Sci
. 2021 Jan;25(2):1097-1100.
doi: 10.26355/eurrev_202101_24680.
The value of PCT, IL-6, and CRP in the early diagnosis and evaluation of COVID-19
Y-Z Zhou[SUP] 1 [/SUP], X-B Teng, M-F Han, J-F Shi, C-X Li, X-H Zhang, D-Y Hou, L-L Yang
Affiliations
Abstract
Objective: The aim of the present study was to assess the value of inflammatory factors procalcitonin (PCT), interleukin 6 (IL-6), and C-reactive protein (CRP) in the early diagnosis and evaluation of novel coronavirus pneumonia (COVID-19).
Materials and methods: The data of 140 patients with pneumonia in our hospital, including 70 who had COVID-19 and 70 who had community-acquired pneumonia (CAP), were statistically analyzed. The levels of PCT, IL-6, and CRP were measured and statistically analyzed to determine the differences between the two groups. The differences in the COVID-19 group were analyzed after subgrouping into the ordinary type, severe type, and critical type.
Results: The PCT and CRP levels in the COVID-19 group were statistically lower than those in the CAP group (p < 0.05), but IL-6 was not statistically different between the two groups (p > 0.05). Statistically significant differences existed in IL-6 and CRP when comparing the COVID-19 subgroups of the critical type, severe type, and ordinary type (p < 0.05). However, there was no clinical meaning in the evaluation of the difference in PCT levels among the three subgroups with COVID-19.
Conclusions: PCT and CRP could be used as indicators in the differentiation between COVID-19 and CAP, but IL-6 was of little significance in the differentiation. The higher the IL-6 and CRP, the more severe the condition of COVID-19 might be.
. 2021 Jan;25(2):1097-1100.
doi: 10.26355/eurrev_202101_24680.
The value of PCT, IL-6, and CRP in the early diagnosis and evaluation of COVID-19
Y-Z Zhou[SUP] 1 [/SUP], X-B Teng, M-F Han, J-F Shi, C-X Li, X-H Zhang, D-Y Hou, L-L Yang
Affiliations
- PMID: 33577066
- DOI: 10.26355/eurrev_202101_24680
Abstract
Objective: The aim of the present study was to assess the value of inflammatory factors procalcitonin (PCT), interleukin 6 (IL-6), and C-reactive protein (CRP) in the early diagnosis and evaluation of novel coronavirus pneumonia (COVID-19).
Materials and methods: The data of 140 patients with pneumonia in our hospital, including 70 who had COVID-19 and 70 who had community-acquired pneumonia (CAP), were statistically analyzed. The levels of PCT, IL-6, and CRP were measured and statistically analyzed to determine the differences between the two groups. The differences in the COVID-19 group were analyzed after subgrouping into the ordinary type, severe type, and critical type.
Results: The PCT and CRP levels in the COVID-19 group were statistically lower than those in the CAP group (p < 0.05), but IL-6 was not statistically different between the two groups (p > 0.05). Statistically significant differences existed in IL-6 and CRP when comparing the COVID-19 subgroups of the critical type, severe type, and ordinary type (p < 0.05). However, there was no clinical meaning in the evaluation of the difference in PCT levels among the three subgroups with COVID-19.
Conclusions: PCT and CRP could be used as indicators in the differentiation between COVID-19 and CAP, but IL-6 was of little significance in the differentiation. The higher the IL-6 and CRP, the more severe the condition of COVID-19 might be.