tetano
Editor, Senior Moderator
Eur Radiol
. 2020 Jun 9;1-8.
doi: 10.1007/s00330-020-06978-4. Online ahead of print.
Early Chest CT Features of Patients With 2019 Novel Coronavirus (COVID-19) Pneumonia: Relationship to Diagnosis and Prognosis
Hui Juan Chen[SUP] 1 [/SUP], Jie Qiu[SUP] 2 [/SUP], Biao Wu[SUP] 3 [/SUP], Tao Huang[SUP] 4 [/SUP], Yunsuo Gao[SUP] 5 [/SUP], Zhen Ping Wang[SUP] 1 [/SUP], Yang Chen[SUP] 1 [/SUP], Feng Chen[SUP] 6 [/SUP]
Affiliations
Abstract
Objective: To determine the consistency between CT findings and real-time reverse transcription-polymerase chain reaction (RT-PCR) and to investigate the relationship between CT features and clinical prognosis in COVID-19.
Methods: The clinical manifestations, laboratory parameters, and CT imaging findings were analyzed in 34 COVID-19 patients, confirmed by RT-PCR from January 20 to February 4 in Hainan Province. CT scores were compared between the discharged patients and the ICU patients.
Results: Fever (85%) and cough (79%) were most commonly seen. Ten (29%) patients demonstrated negative results on their first RT-PCR. Of the 34 (65%) patients, 22 showed pure ground-glass opacity. Of the 34 (50%) patients, 17 had five lobes of lung involvement, while the 23 (68%) patients had lower lobe involvement. The lesions of 24 (71%) patients were distributed mainly in the subpleural area. The initial CT lesions of ICU patients were distributed in both the subpleural area and centro-parenchyma (80%), and the lesions were scattered. Sixty percent of ICU patients had five lobes involved, while this was seen in only 25% of the discharged patients. The lesions of discharged patients were mainly in the subpleural area (75%). Of the discharged patients, 62.5% showed pure ground-glass opacities; 80% of the ICU patients were in the progressive stage, and 75% of the discharged patients were at an early stage. CT scores of the ICU patients were significantly higher than those of the discharged patients.
Conclusion: Chest CT plays a crucial role in the early diagnosis of COVID-19, particularly for those patients with a negative RT-PCR. The initial features in CT may be associated with prognosis.
Key points: • Chest CT is valuable for the early diagnosis of COVID-19, particularly for those patients with a negative RT-PCR. • The early CT findings of COVID-19 in ICU patients differed from those of discharged patients.
Keywords: COVID-19; Pneumonia; Thorax; Tomography.
. 2020 Jun 9;1-8.
doi: 10.1007/s00330-020-06978-4. Online ahead of print.
Early Chest CT Features of Patients With 2019 Novel Coronavirus (COVID-19) Pneumonia: Relationship to Diagnosis and Prognosis
Hui Juan Chen[SUP] 1 [/SUP], Jie Qiu[SUP] 2 [/SUP], Biao Wu[SUP] 3 [/SUP], Tao Huang[SUP] 4 [/SUP], Yunsuo Gao[SUP] 5 [/SUP], Zhen Ping Wang[SUP] 1 [/SUP], Yang Chen[SUP] 1 [/SUP], Feng Chen[SUP] 6 [/SUP]
Affiliations
- PMID: 32518987
- PMCID: PMC7280678
- DOI: 10.1007/s00330-020-06978-4
Abstract
Objective: To determine the consistency between CT findings and real-time reverse transcription-polymerase chain reaction (RT-PCR) and to investigate the relationship between CT features and clinical prognosis in COVID-19.
Methods: The clinical manifestations, laboratory parameters, and CT imaging findings were analyzed in 34 COVID-19 patients, confirmed by RT-PCR from January 20 to February 4 in Hainan Province. CT scores were compared between the discharged patients and the ICU patients.
Results: Fever (85%) and cough (79%) were most commonly seen. Ten (29%) patients demonstrated negative results on their first RT-PCR. Of the 34 (65%) patients, 22 showed pure ground-glass opacity. Of the 34 (50%) patients, 17 had five lobes of lung involvement, while the 23 (68%) patients had lower lobe involvement. The lesions of 24 (71%) patients were distributed mainly in the subpleural area. The initial CT lesions of ICU patients were distributed in both the subpleural area and centro-parenchyma (80%), and the lesions were scattered. Sixty percent of ICU patients had five lobes involved, while this was seen in only 25% of the discharged patients. The lesions of discharged patients were mainly in the subpleural area (75%). Of the discharged patients, 62.5% showed pure ground-glass opacities; 80% of the ICU patients were in the progressive stage, and 75% of the discharged patients were at an early stage. CT scores of the ICU patients were significantly higher than those of the discharged patients.
Conclusion: Chest CT plays a crucial role in the early diagnosis of COVID-19, particularly for those patients with a negative RT-PCR. The initial features in CT may be associated with prognosis.
Key points: • Chest CT is valuable for the early diagnosis of COVID-19, particularly for those patients with a negative RT-PCR. • The early CT findings of COVID-19 in ICU patients differed from those of discharged patients.
Keywords: COVID-19; Pneumonia; Thorax; Tomography.