tetano
Editor, Senior Moderator
Eur J Obstet Gynecol Reprod Biol
. 2020 Dec 1;256:400-404.
doi: 10.1016/j.ejogrb.2020.11.069. Online ahead of print.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) universal screening in gravids during labor and delivery
Ricardo Savir?n-Cornudella[SUP] 1 [/SUP], Ana Villalba[SUP] 2 [/SUP], Javier Zapardiel[SUP] 3 [/SUP], Mercedes Andeyro-Garcia[SUP] 2 [/SUP], Luis M Esteban[SUP] 4 [/SUP], Faustino R P?rez-L?pez[SUP] 5 [/SUP]
Affiliations
Abstract
Objective: To screen pregnant women at risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during delivery using reverse-transcription polymerase chain reaction (RT-PCR) test and serum immunoglobulin (Ig) testing.
Method: Between March 31 st and August 31 st of 2020, consecutive pregnant women admitted for labor and delivery in a single hospital were screened for SARS-CoV-2 with nasopharyngeal RT-PCR swab tests and detection of serum IgG and IgM.
Results: We studied 266 pregnant women admitted for labor and delivery. The prevalence of acute or past SARS-CoV-2 infection was 9.0 %, including (i) two cases with respiratory symptoms of SARS-Co-V-2 infection and positive RT-PCR; (ii) four asymptomatic women with positive RT-PCR without clinical symptoms and negative serological tests between two and 15 weeks later; and (iii) two women with false positive RT-PCR due to technical problems. All newborns of the 6 pregnant women with RT-PCR positive had negative RT-PCR and did not require Neonatal Intensive Care Unit admission. There were eighteen asymptomatic women with positive serological IgG tests and negative RT-PCR.
Conclusion: In our cohort of gravids, we found 2.2 % of women with positive RT-PRC tests and 6.7 % with positive serological tests during the first wave of the SARS-CoV-2 pandemic.
Keywords: COVID-19; Delivery; Reverse-transcription polymerase chain reaction (RT-PCR); SARS-CoV-2; Screening; serum immunoglobulins.
. 2020 Dec 1;256:400-404.
doi: 10.1016/j.ejogrb.2020.11.069. Online ahead of print.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) universal screening in gravids during labor and delivery
Ricardo Savir?n-Cornudella[SUP] 1 [/SUP], Ana Villalba[SUP] 2 [/SUP], Javier Zapardiel[SUP] 3 [/SUP], Mercedes Andeyro-Garcia[SUP] 2 [/SUP], Luis M Esteban[SUP] 4 [/SUP], Faustino R P?rez-L?pez[SUP] 5 [/SUP]
Affiliations
- PMID: 33285496
- DOI: 10.1016/j.ejogrb.2020.11.069
Abstract
Objective: To screen pregnant women at risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during delivery using reverse-transcription polymerase chain reaction (RT-PCR) test and serum immunoglobulin (Ig) testing.
Method: Between March 31 st and August 31 st of 2020, consecutive pregnant women admitted for labor and delivery in a single hospital were screened for SARS-CoV-2 with nasopharyngeal RT-PCR swab tests and detection of serum IgG and IgM.
Results: We studied 266 pregnant women admitted for labor and delivery. The prevalence of acute or past SARS-CoV-2 infection was 9.0 %, including (i) two cases with respiratory symptoms of SARS-Co-V-2 infection and positive RT-PCR; (ii) four asymptomatic women with positive RT-PCR without clinical symptoms and negative serological tests between two and 15 weeks later; and (iii) two women with false positive RT-PCR due to technical problems. All newborns of the 6 pregnant women with RT-PCR positive had negative RT-PCR and did not require Neonatal Intensive Care Unit admission. There were eighteen asymptomatic women with positive serological IgG tests and negative RT-PCR.
Conclusion: In our cohort of gravids, we found 2.2 % of women with positive RT-PRC tests and 6.7 % with positive serological tests during the first wave of the SARS-CoV-2 pandemic.
Keywords: COVID-19; Delivery; Reverse-transcription polymerase chain reaction (RT-PCR); SARS-CoV-2; Screening; serum immunoglobulins.