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Eur J Med Res . Comparison of the clinical outcomes of COVID-19 in pregnant and non-pregnant patients of reproductive age

tetano

Editor, Senior Moderator
Eur J Med Res


. 2025 Jul 29;30(1):681.
doi: 10.1186/s40001-025-02733-x. Comparison of the clinical outcomes of COVID-19 in pregnant and non-pregnant patients of reproductive age

Nazila Karzad[SUP] 1 [/SUP], Simin Taghavi[SUP] 2 [/SUP], Ata Mahmoodpoor[SUP] 3 [/SUP], Seied Hadi Saghaleini[SUP] 4 [/SUP], Saeid Safiri[SUP] 5 [/SUP], Pouya Hosseinzadeh[SUP] 6 [/SUP]



Affiliations
Abstract

Purpose: This study aims to compare the clinical course of COVID-19 in pregnant versus non-pregnant women aged 15-45 in Tabriz, focusing on disease severity, mortality, and pregnancy outcomes.
Methods: A total of 300 women were analyzed, with 150 pregnant and 150 non-pregnant participants. Data collected included demographic information, comorbidities, clinical outcomes, and pregnancy-related complications.
Results: The mean age of pregnant women was 32 years, while non-pregnant women averaged 38 years. Common comorbidities in the pregnant group included gestational diabetes and hypertension. Pregnant women predominantly experienced mild COVID-19 cases, whereas severe cases were more frequent in non-pregnant women; however, these differences were not statistically significant. Both groups had a mortality rate of 4.7%, with seven deaths reported in each cohort. Among pregnant women, 19% experienced preterm births, 6.7% had miscarriages, 3.5% had stillbirths, and 6.7% faced postpartum hemorrhages, with most preterm births being induced.
Conclusions: The findings suggest that pregnancy does not worsen the clinical course of COVID-19, as pregnant women generally exhibit milder symptoms and require fewer intensive care unit admissions compared to their non-pregnant counterparts.

Keywords: COVID-19; Morbidity; Mortality; Pregnancy; Women.

 
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