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Eur J Immunol . T Cell Response Evaluation After A Fifth Dose of an Inactivated SARS-CoV-2 Vaccine Using Multiparametric Flow Cytometry

tetano

tetano

Editor, Senior Moderator
Eur J Immunol


. 2025 Jul;55(7):e51848.
doi: 10.1002/eji.202551848. T Cell Response Evaluation After A Fifth Dose of an Inactivated SARS-CoV-2 Vaccine Using Multiparametric Flow Cytometry

Francisca Román[SUP] 1 [/SUP], Antonia Reyes[SUP] 1 [/SUP], Cristián Gutiérrez[SUP] 2 [/SUP], Linmar Rodríguez-Guilarte[SUP] 1 [/SUP], Constanza Méndez[SUP] 1 [/SUP], Daniela Moreno-Tapia[SUP] 1 [/SUP], Mariana Ríos[SUP] 1 [/SUP], Alex Cabrera[SUP] 3 [/SUP], Leandro J Carreño[SUP] 2 [/SUP], Pablo A González[SUP] 1 [/SUP], Susan M Bueno[SUP] 1 [/SUP], Alexis M Kalergis[SUP] 1 4 [/SUP], Hernán F Peñaloza[SUP] 1 5 [/SUP]



Affiliations
Abstract

The T cell response induced by SARS-CoV-2 vaccines is an essential component of immune protection against COVID-19. Multiparametric flow cytometry analysis emerges as a valuable tool for in-depth assessment of T cell phenotype nuances that occur after booster vaccination, such as a fifth dose of an inactivated SARS-CoV-2 vaccine. Figure created with BioRender.com.

Keywords: COVID‐19 vaccine; cellular immunity; multiparametric flow cytometry.

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