• FluTrackers.com Inc. does not provide medical advice. Information on this web site is collected from various internet resources, and the FluTrackers board of directors makes no warranty to the safety, efficacy, correctness or completeness of the information posted on this site by any author or poster. The information collated here is for instructional and/or discussion purposes only and is NOT intended to diagnose or treat any disease, illness, or other medical condition. Every individual reader or poster should seek advice from their personal physician/healthcare practitioner before considering or using any interventions that are discussed on this website. By continuing to access this website you agree to consult your personal physican before using any interventions posted on this website, and you agree to hold harmless FluTrackers.com Inc., the board of directors, the members, and all authors and posters for any effects from use of any medication, supplement, vitamin or other substance, device, intervention, etc. mentioned in posts on this website, or other internet venues referenced in posts on this website.
  • We are not asking for any donations. Do not donate to any entity who says they are raising funds for us.

Eur J Heart Fail. Myocardial localization of coronavirus in COVID-19 cardiogenic shock

tetano

Editor, Senior Moderator
Eur J Heart Fail. 2020 Apr 10. doi: 10.1002/ejhf.1828. [Epub ahead of print]
Myocardial localization of coronavirus in COVID-19 cardiogenic shock.


Tavazzi G[SUP]1,[/SUP][SUP]2[/SUP], Pellegrini C[SUP]1,[/SUP][SUP]3[/SUP], Maurelli M[SUP]4[/SUP], Belliato M[SUP]2[/SUP], Sciutti F[SUP]2[/SUP], Bottazzi A[SUP]2[/SUP], Sepe PA[SUP]5[/SUP], Resasco T[SUP]5[/SUP], Camporotondo R[SUP]6[/SUP], Bruno R[SUP]1,[/SUP][SUP]7[/SUP], Baldanti F[SUP]1,[/SUP][SUP]8[/SUP], Paolucci S[SUP]8[/SUP], Pelenghi S[SUP]3[/SUP], Iotti GA[SUP]1,[/SUP][SUP]2[/SUP], Mojoli F[SUP]1,[/SUP][SUP]2[/SUP], Arbustini E[SUP]9[/SUP].

Author information




Abstract

We describe the first case of acute cardiac injury directly linked to myocardial localization of severe acute respiratory syndrome coronavirus (SARS-CoV-2) in a 69-year-old patient with flu-like symptoms rapidly degenerating into respiratory distress, hypotension, and cardiogenic shock. The patient was successfully treated with venous-arterial extracorporeal membrane oxygenation (ECMO) and mechanical ventilation. Cardiac function fully recovered in 5 days and ECMO was removed. Endomyocardial biopsy demonstrated low-grade myocardial inflammation and viral particles in the myocardium suggesting either a viraemic phase or, alternatively, infected macrophage migration from the lung.
? 2020 European Society of Cardiology.



KEYWORDS:

Cardiac injury; Cardiogenic shock; Coronavirus; Extracorporeal membrane oxygenation; Myocardial inflammation; SARS-CoV-2


PMID:32275347DOI:10.1002/ejhf.1828
 
Back
Top