tetano
Editor, Senior Moderator
Eur J Clin Microbiol Infect Dis
. 2024 Jul 20.
doi: 10.1007/s10096-024-04897-6. Online ahead of print. Pulmonary microbial spectrum in late-stage SARS-CoV-2 infection: a case series
Jin-Jing Hong[SUP] #[/SUP][SUP] 1 [/SUP], Ren-Tao Zhang[SUP] #[/SUP][SUP] 1 [/SUP], Chun-Lian Ma[SUP] 2 [/SUP], Qiong-Ying Hu[SUP] 3 [/SUP]
Affiliations
Coronavirus disease 2019 (COVID-19), a kind of respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), primarily spreads through the respiratory tract from human to human. Its extensive and rapid spread has led to a global pandemic, causing great harm to human health and economic development all over the world. Current known evidence indicates that SARS-CoV-2 has evolved accumulating multiple mutations, with altered infectivity and viral replication capacity. A better understanding of the complications of COVID-19 and its relationship with underlying diseases is crucial for the prevention and treatment of SARS-CoV-2. This case series reviewed case data of our 4 recent patients with severe or critical COVID-19, including treatment plan, status of pulmonary infection and their microbiology workup with metagenomic next-generation sequencing with bronchoalveolar lavage fluid. This report shed light on the significance of rapid and accurate clinical diagnosis and treatment on COVID-19.
Keywords: SARS-CoV-2; COVID-19; Clinical diagnosis and treatment; Severe and critical pneumonia; mNGS.
. 2024 Jul 20.
doi: 10.1007/s10096-024-04897-6. Online ahead of print. Pulmonary microbial spectrum in late-stage SARS-CoV-2 infection: a case series
Jin-Jing Hong[SUP] #[/SUP][SUP] 1 [/SUP], Ren-Tao Zhang[SUP] #[/SUP][SUP] 1 [/SUP], Chun-Lian Ma[SUP] 2 [/SUP], Qiong-Ying Hu[SUP] 3 [/SUP]
Affiliations
- PMID: 39031269
- DOI: 10.1007/s10096-024-04897-6
Coronavirus disease 2019 (COVID-19), a kind of respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), primarily spreads through the respiratory tract from human to human. Its extensive and rapid spread has led to a global pandemic, causing great harm to human health and economic development all over the world. Current known evidence indicates that SARS-CoV-2 has evolved accumulating multiple mutations, with altered infectivity and viral replication capacity. A better understanding of the complications of COVID-19 and its relationship with underlying diseases is crucial for the prevention and treatment of SARS-CoV-2. This case series reviewed case data of our 4 recent patients with severe or critical COVID-19, including treatment plan, status of pulmonary infection and their microbiology workup with metagenomic next-generation sequencing with bronchoalveolar lavage fluid. This report shed light on the significance of rapid and accurate clinical diagnosis and treatment on COVID-19.
Keywords: SARS-CoV-2; COVID-19; Clinical diagnosis and treatment; Severe and critical pneumonia; mNGS.