tetano
Editor, Senior Moderator
Eur J Clin Microbiol Infect Dis
. 2020 Aug 31.
doi: 10.1007/s10096-020-04024-1. Online ahead of print.
Prevalence and outcomes of re-positive nucleic acid tests in discharged COVID-19 patients
Hou-Wei Du[SUP] 1 [/SUP], Jun-Nian Chen[SUP] 2 [/SUP], Xiao-Bin Pan[SUP] 3 [/SUP], Xiao-Ling Chen[SUP] 4 [/SUP], Yixian-Zhang[SUP] 5 [/SUP], Shuang-Fang Fang[SUP] 1 [/SUP], Xiao-Qing Li[SUP] 6 [/SUP], Pin-Cang Xia[SUP] 6 [/SUP], Lei Gao[SUP] 7 [/SUP], Hai-Long Lin[SUP] 8 [/SUP], Li-Min Chen[SUP] 9 [/SUP], Nan Liu[SUP] 10 [/SUP], Fujian Medical Team Support Wuhan for COVID-19
Affiliations
Abstract
The prevalence and outcomes of patients who had re-activation of coronavirus disease 2019 (COVID-19) after discharge remain poorly understood. We included 126 consecutively confirmed cases of COVID-19 with 2-month follow-up data after discharge in this retrospective study. The upper respiratory specimen using a reverse-transcription polymerase chain reaction test of three patients (71 years [60-76]) were positive within 11-20 days after their discharge, with an event rate of 19.8 (95%CI 2.60-42.1) per 1,000,000 patient-days. Moreover, all re-positive patients were asymptomatic. Our findings suggest that few recovered patients may still be virus carriers even after reaching the discharge criteria.
Keywords: Coronavirus disease 2019; Follow-up; Infectivity; Outcome; Re-positive.
. 2020 Aug 31.
doi: 10.1007/s10096-020-04024-1. Online ahead of print.
Prevalence and outcomes of re-positive nucleic acid tests in discharged COVID-19 patients
Hou-Wei Du[SUP] 1 [/SUP], Jun-Nian Chen[SUP] 2 [/SUP], Xiao-Bin Pan[SUP] 3 [/SUP], Xiao-Ling Chen[SUP] 4 [/SUP], Yixian-Zhang[SUP] 5 [/SUP], Shuang-Fang Fang[SUP] 1 [/SUP], Xiao-Qing Li[SUP] 6 [/SUP], Pin-Cang Xia[SUP] 6 [/SUP], Lei Gao[SUP] 7 [/SUP], Hai-Long Lin[SUP] 8 [/SUP], Li-Min Chen[SUP] 9 [/SUP], Nan Liu[SUP] 10 [/SUP], Fujian Medical Team Support Wuhan for COVID-19
Affiliations
- PMID: 32865669
- DOI: 10.1007/s10096-020-04024-1
Abstract
The prevalence and outcomes of patients who had re-activation of coronavirus disease 2019 (COVID-19) after discharge remain poorly understood. We included 126 consecutively confirmed cases of COVID-19 with 2-month follow-up data after discharge in this retrospective study. The upper respiratory specimen using a reverse-transcription polymerase chain reaction test of three patients (71 years [60-76]) were positive within 11-20 days after their discharge, with an event rate of 19.8 (95%CI 2.60-42.1) per 1,000,000 patient-days. Moreover, all re-positive patients were asymptomatic. Our findings suggest that few recovered patients may still be virus carriers even after reaching the discharge criteria.
Keywords: Coronavirus disease 2019; Follow-up; Infectivity; Outcome; Re-positive.