tetano
Editor, Senior Moderator
Eur J Clin Microbiol Infect Dis
. 2021 Mar 6.
doi: 10.1007/s10096-021-04217-2. Online ahead of print.
Comparison of clinical characteristics and outcomes between respiratory syncytial virus and influenza-related pneumonia in China from 2013 to 2019
Liang Chen[SUP] 1 [/SUP], Xiudi Han[SUP] 2 [/SUP], YanLi Li[SUP] 3 [/SUP], Chunxiao Zhang[SUP] 4 [/SUP], Xiqian Xing[SUP] 5 [/SUP]
Affiliations
Abstract
This study aims to compare clinical characteristics and severity between adults with respiratory syncytial virus (RSV-p) and influenza-related pneumonia (Flu-p). A total of 127 patients with RSV-p, 693 patients with influenza A-related pneumonia (FluA-p), and 386 patients with influenza B-related pneumonia (FluB-p) were retrospectively reviewed from 2013 through 2019 in five teaching hospitals in China. A multivariate logistic regression model indicated that age ? 50 years, cerebrovascular disease, chronic kidney disease, solid malignant tumor, nasal congestion, myalgia, sputum production, respiratory rates ? 30 beats/min, lymphocytes < 0.8?10[SUP]9[/SUP]/L, and blood albumin < 35 g/L were predictors that differentiated RSV-p from Flu-p. After adjusting for confounders, a multivariate logistic regression analysis confirmed that, relative to RSV-p, FluA-p (OR 2.313, 95% CI 1.377-3.885, p = 0.002) incurred an increased risk for severe outcomes, including invasive ventilation, ICU admission, and 30-day mortality; FluB-p (OR 1.630, 95% CI 0.958-2.741, p = 0.071) was not associated with increased risk. Some clinical variables were useful for discriminating RSV-p from Flu-p. The severity of RSV-p was less than that of FluA-p, but was comparable to FluB-p.
Keywords: Clinical characteristic; Influenza virus; Outcome; Pneumonia; Respiratory syncytial virus.
. 2021 Mar 6.
doi: 10.1007/s10096-021-04217-2. Online ahead of print.
Comparison of clinical characteristics and outcomes between respiratory syncytial virus and influenza-related pneumonia in China from 2013 to 2019
Liang Chen[SUP] 1 [/SUP], Xiudi Han[SUP] 2 [/SUP], YanLi Li[SUP] 3 [/SUP], Chunxiao Zhang[SUP] 4 [/SUP], Xiqian Xing[SUP] 5 [/SUP]
Affiliations
- PMID: 33677754
- DOI: 10.1007/s10096-021-04217-2
Abstract
This study aims to compare clinical characteristics and severity between adults with respiratory syncytial virus (RSV-p) and influenza-related pneumonia (Flu-p). A total of 127 patients with RSV-p, 693 patients with influenza A-related pneumonia (FluA-p), and 386 patients with influenza B-related pneumonia (FluB-p) were retrospectively reviewed from 2013 through 2019 in five teaching hospitals in China. A multivariate logistic regression model indicated that age ? 50 years, cerebrovascular disease, chronic kidney disease, solid malignant tumor, nasal congestion, myalgia, sputum production, respiratory rates ? 30 beats/min, lymphocytes < 0.8?10[SUP]9[/SUP]/L, and blood albumin < 35 g/L were predictors that differentiated RSV-p from Flu-p. After adjusting for confounders, a multivariate logistic regression analysis confirmed that, relative to RSV-p, FluA-p (OR 2.313, 95% CI 1.377-3.885, p = 0.002) incurred an increased risk for severe outcomes, including invasive ventilation, ICU admission, and 30-day mortality; FluB-p (OR 1.630, 95% CI 0.958-2.741, p = 0.071) was not associated with increased risk. Some clinical variables were useful for discriminating RSV-p from Flu-p. The severity of RSV-p was less than that of FluA-p, but was comparable to FluB-p.
Keywords: Clinical characteristic; Influenza virus; Outcome; Pneumonia; Respiratory syncytial virus.