tetano
Editor, Senior Moderator
Eur J Case Rep Intern Med
. 2020 Dec 29;7(12):002145.
doi: 10.12890/2020_002145. eCollection 2020.
Is Persistent Thick Copious Mucus a Long-Term Symptom of COVID-19?
Patrick Manckoundia[SUP] 1 2 [/SUP], Evelyne Franon[SUP] 3 [/SUP]
Affiliations
Abstract
Introduction: The typical clinical picture of COVID-19 is gradually becoming clearer, both in the acute phase and in the long-term. However, new symptoms are gradually being identified. We describe a long-term symptom that has not yet been reported.
Case description: A 49-year-old man consulted for persistent asthenia. The general practitioner found a fever (39.2?C), and COVID-19 was confirmed by the polymerase chain reaction test. Further symptoms appeared, notably thick, white, painless tracheal hypersecretion for 3 months before diminishing, without disappearing.
Conclusion: Non-inflammatory tracheal hypersecretion, not yet reported in COVID-19, may be an additional long-term symptom. The hyperstimulation of tracheal goblet cells secreting mucus is 1 pathophysiological hypothesis.
Learning points: Painless, non-inflammatory tracheal hypersecretion, which has yet to be described in post-acute COVID-19, may be an additional long-term symptom of the disease.The hyperstimulation of mucus-secreting tracheal goblet cells by the coronavirus, leading to tracheal discomfort and a feeling of suffocation, is 1 pathophysiological hypothesis.
Keywords: COVID-19; long-term symptom; tracheal hypersecretion.
. 2020 Dec 29;7(12):002145.
doi: 10.12890/2020_002145. eCollection 2020.
Is Persistent Thick Copious Mucus a Long-Term Symptom of COVID-19?
Patrick Manckoundia[SUP] 1 2 [/SUP], Evelyne Franon[SUP] 3 [/SUP]
Affiliations
- PMID: 33457378
- PMCID: PMC7806295
- DOI: 10.12890/2020_002145
Abstract
Introduction: The typical clinical picture of COVID-19 is gradually becoming clearer, both in the acute phase and in the long-term. However, new symptoms are gradually being identified. We describe a long-term symptom that has not yet been reported.
Case description: A 49-year-old man consulted for persistent asthenia. The general practitioner found a fever (39.2?C), and COVID-19 was confirmed by the polymerase chain reaction test. Further symptoms appeared, notably thick, white, painless tracheal hypersecretion for 3 months before diminishing, without disappearing.
Conclusion: Non-inflammatory tracheal hypersecretion, not yet reported in COVID-19, may be an additional long-term symptom. The hyperstimulation of tracheal goblet cells secreting mucus is 1 pathophysiological hypothesis.
Learning points: Painless, non-inflammatory tracheal hypersecretion, which has yet to be described in post-acute COVID-19, may be an additional long-term symptom of the disease.The hyperstimulation of mucus-secreting tracheal goblet cells by the coronavirus, leading to tracheal discomfort and a feeling of suffocation, is 1 pathophysiological hypothesis.
Keywords: COVID-19; long-term symptom; tracheal hypersecretion.