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Eur Heart J . Myopericardial complications following COVID-19 disease and vaccination: a clinical consensus statement of the European Society of Ca

tetano

Editor, Senior Moderator
Eur Heart J


. 2025 May 20:ehaf222.
doi: 10.1093/eurheartj/ehaf222. Online ahead of print. Myopericardial complications following COVID-19 disease and vaccination: a clinical consensus statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases

Massimo Imazio[SUP] 1 2 [/SUP], Cristina Basso[SUP] 3 [/SUP], Antonio Brucato[SUP] 4 [/SUP], Karin Klingel[SUP] 5 [/SUP], Petr Kuchynka[SUP] 6 [/SUP], George Lazaros[SUP] 7 [/SUP], Marco Merlo[SUP] 8 9 [/SUP], Gianfranco Sinagra[SUP] 8 9 [/SUP], Yehuda Adler[SUP] 10 [/SUP], Chiara Bucciarelli Ducci[SUP] 11 [/SUP], Matteo Cameli[SUP] 12 [/SUP], Silvia Castelletti[SUP] 13 14 [/SUP], Alida Linda Caforio[SUP] 15 [/SUP], Lia Crotti[SUP] 13 14 [/SUP], Lorenzo Dagna[SUP] 16 17 [/SUP], Andrea Frustaci[SUP] 18 [/SUP], Allan Klein[SUP] 19 [/SUP], Johanna Kuusisto[SUP] 20 [/SUP], Angela Lopez Sainz[SUP] 21 [/SUP], Renzo Marcolongo[SUP] 15 [/SUP], Antonis Pantazis[SUP] 22 [/SUP], Angelos G Rigopoulos[SUP] 23 [/SUP], Arsen Ristic[SUP] 24 [/SUP], Petar Seferovic[SUP] 25 [/SUP], Mary Sheppard[SUP] 26 [/SUP], Carsten Tschöpe[SUP] 27 28 29 [/SUP], Thomas Lüscher[SUP] 30 31 [/SUP]



Affiliations
Abstract

The aim of the present clinical consensus statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases is to review the current knowledge on the epidemiology, pathogenesis, diagnosis, therapy, and outcomes of myocardial and pericardial complications of coronavirus disease 2019 (COVID-19) and vaccination in order to improve the awareness and clinical confidence on the management of patients with these complications. The risk of myopericardial complications is especially higher within 1 month of COVID-19 disease and vaccination. Forms related to the disease are generally more common and severe than those related to vaccination. Even if vaccination against COVID-19 increases myocarditis risk, this risk is lower in vaccinated than non-vaccinated COVID-19 individuals, supporting the vaccine use. Overall, COVID-19 related complications, especially myocarditis, are relatively rare.

Keywords: COVID-19; Myocarditis; Pericardial effusion; Pericarditis.

 
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