tetano
Editor, Senior Moderator
Eur Heart J Case Rep
. 2020 Dec 29;5(2):ytaa518.
doi: 10.1093/ehjcr/ytaa518. eCollection 2021 Feb.
Unusual intracardiac thrombosis in two patients with coronavirus disease 2019 (COVID-19): case series
Emiliano Calvi[SUP] 1 [/SUP], Nicola Bernardi[SUP] 1 [/SUP], Giuliana Cimino[SUP] 1 [/SUP], Greta Pascariello[SUP] 1 [/SUP], Pompilio Faggiano[SUP] 1 [/SUP], Emanuele Gavazzi[SUP] 2 [/SUP], Enrico Vizzardi[SUP] 1 [/SUP], Marco Metra[SUP] 1 [/SUP]
Affiliations
Abstract
Background: COVID-19 may induce a coagulation dysregulation resulting in a prothrombotic state with a higher risk of arterial and venous thrombosis. This abnormal thrombotic diathesis can lead to pulmonary embolism, stroke, and intracardiac thrombosis.
Case summary: We present two cases of unusual intracardiac thrombosis in patients hospitalized for COVID-19. In both cases, imaging tests (such as transthoracic echocardiography (TTE), computed tomography scan of the chest, and cardiac magnetic resonance imaging) showed evidence of unusual intracardiac thrombosis with thrombi adherent to regularly contracting walls.
Discussion: This evidence confirms that COVID-19 induces a hypercoagulable state which can result in intracardiac thrombosis. Therefore, TTE is indicated in all COVID-19 patients for early diagnosis, and prompt anticoagulant therapy is to be considered as a thromboprophylaxis strategy.
Keywords: Anticoagulant; Case series; Coagulation; Thrombus; Transthoracic echocardiography.
. 2020 Dec 29;5(2):ytaa518.
doi: 10.1093/ehjcr/ytaa518. eCollection 2021 Feb.
Unusual intracardiac thrombosis in two patients with coronavirus disease 2019 (COVID-19): case series
Emiliano Calvi[SUP] 1 [/SUP], Nicola Bernardi[SUP] 1 [/SUP], Giuliana Cimino[SUP] 1 [/SUP], Greta Pascariello[SUP] 1 [/SUP], Pompilio Faggiano[SUP] 1 [/SUP], Emanuele Gavazzi[SUP] 2 [/SUP], Enrico Vizzardi[SUP] 1 [/SUP], Marco Metra[SUP] 1 [/SUP]
Affiliations
- PMID: 34192222
- PMCID: PMC7953950
- DOI: 10.1093/ehjcr/ytaa518
Abstract
Background: COVID-19 may induce a coagulation dysregulation resulting in a prothrombotic state with a higher risk of arterial and venous thrombosis. This abnormal thrombotic diathesis can lead to pulmonary embolism, stroke, and intracardiac thrombosis.
Case summary: We present two cases of unusual intracardiac thrombosis in patients hospitalized for COVID-19. In both cases, imaging tests (such as transthoracic echocardiography (TTE), computed tomography scan of the chest, and cardiac magnetic resonance imaging) showed evidence of unusual intracardiac thrombosis with thrombi adherent to regularly contracting walls.
Discussion: This evidence confirms that COVID-19 induces a hypercoagulable state which can result in intracardiac thrombosis. Therefore, TTE is indicated in all COVID-19 patients for early diagnosis, and prompt anticoagulant therapy is to be considered as a thromboprophylaxis strategy.
Keywords: Anticoagulant; Case series; Coagulation; Thrombus; Transthoracic echocardiography.