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Editor, Senior Moderator
J Trop Pediatr. 2017 Nov 3. doi: 10.1093/tropej/fmx087. [Epub ahead of print]
[h=1]Estimation of Burden of Influenza among under-Five Children in India: A Meta-Analysis.[/h] Ram Purakayastha D[SUP]1[/SUP], Vishnubhatla S[SUP]2[/SUP], Rai SK[SUP]1[/SUP], Broor S[SUP]3[/SUP], Krishnan A[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]Background:[/h] We estimated the burden of influenza-related acute respiratory tract infection (ARI) among under-fives in India through meta-analysis.
[h=4]Methodology:[/h] We estimated pooled incidence and proportional positivity of laboratory-diagnosed influenza among under-fives using data from observational studies published from 1 January 1961 to 31 December 2016. Death due to influenza was estimated using a multiplier model.
[h=4]Results:[/h] Influenza-associated ARI incidence was estimated as 132 per 1000 child-years (115-149). The patients positive for influenza among ARI in outpatients and inpatients were estimated to be 11.2% (8.8-13.6) and 7.1% (5.5-8.8), respectively. We estimated total influenza cases during 2016 as 16 009 207 (13 942 916-18 082 769) in India. Influenza accounted for 10 913 476 (9 504 666-12 362 310) outpatient visits and 109 431 (83 882-134 980) hospitalizations. A total of 27 825 (21 382-34 408) influenza-associated under-five deaths were estimated in India in 2016.
[h=4]Conclusion:[/h] Influenza imposes a substantial burden among under-fives in India. Public health approach for its prevention and control needs to be explored.
[h=4]KEYWORDS:[/h] death; hospitalization; influenza; meta-analysis; outpatients; review
PMID: 29112737 DOI: 10.1093/tropej/fmx087
[h=1]Estimation of Burden of Influenza among under-Five Children in India: A Meta-Analysis.[/h] Ram Purakayastha D[SUP]1[/SUP], Vishnubhatla S[SUP]2[/SUP], Rai SK[SUP]1[/SUP], Broor S[SUP]3[/SUP], Krishnan A[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]Background:[/h] We estimated the burden of influenza-related acute respiratory tract infection (ARI) among under-fives in India through meta-analysis.
[h=4]Methodology:[/h] We estimated pooled incidence and proportional positivity of laboratory-diagnosed influenza among under-fives using data from observational studies published from 1 January 1961 to 31 December 2016. Death due to influenza was estimated using a multiplier model.
[h=4]Results:[/h] Influenza-associated ARI incidence was estimated as 132 per 1000 child-years (115-149). The patients positive for influenza among ARI in outpatients and inpatients were estimated to be 11.2% (8.8-13.6) and 7.1% (5.5-8.8), respectively. We estimated total influenza cases during 2016 as 16 009 207 (13 942 916-18 082 769) in India. Influenza accounted for 10 913 476 (9 504 666-12 362 310) outpatient visits and 109 431 (83 882-134 980) hospitalizations. A total of 27 825 (21 382-34 408) influenza-associated under-five deaths were estimated in India in 2016.
[h=4]Conclusion:[/h] Influenza imposes a substantial burden among under-fives in India. Public health approach for its prevention and control needs to be explored.
[h=4]KEYWORDS:[/h] death; hospitalization; influenza; meta-analysis; outpatients; review
PMID: 29112737 DOI: 10.1093/tropej/fmx087