tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2019 Aug 21. doi: 10.1111/irv.12676. [Epub ahead of print]
[h=1]Estimates of influenza-associated hospitalisations in tropical Singapore, 2010-2017: Higher burden estimated in more recent years.[/h] Ng Y[SUP]1[/SUP], Chua LAV[SUP]1[/SUP], Ma S[SUP]1[/SUP], Jian Ming Lee V[SUP]2[/SUP].
[h=3]Author information[/h] 1 Epidemiology and Disease Control Division, Ministry of Health, Singapore City, Singapore. 2 Communicable Diseases Division, Ministry of Health, Singapore City, Singapore.
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] We previously estimated Singapore's influenza-associated hospitalisation rate for pneumonia and influenza (P&I) in 2010-2012 to be 29.6 per 100 000 person-years, which corresponds to 11.2% of all P&I hospitalisations.
[h=4]OBJECTIVES:[/h] This study aims to update Singapore's estimates of the influenza-associated pneumonia and influenza (P&I) hospitalisation burden using the latest data from 2010 to 2017.
[h=4]METHODS:[/h] We estimated the number of P&I hospitalisations associated with influenza using generalised additive models. We specified the weekly number of admissions for P&I and the weekly influenza positivity in the models, along with potential confounders such as weekly respiratory syncytial virus (RSV) positivity and meteorological data.
[h=4]RESULTS:[/h] In 2010-2017, 16.3% of all P&I hospitalisations in Singapore were estimated to be attributed to influenza, corresponding to an excess influenza-associated P&I hospitalisation rate of 50.1 per 100 000 person-years. Higher excess rates were estimated for children aged 0-4 years (186.8 per 100 000 person-years) and elderly aged ≥ 65 years (338.0 per 100 000 person-years). Higher influenza-associated hospitalisation rates were estimated for 2016 and 2017 (67.9 and 75.1 per 100 000 persons, respectively) years when the influenza A(H3N2) subtype was dominant.
[h=4]CONCLUSION:[/h] Influenza burden in Singapore has increased since 2010. Influenza vaccination programmes should continue to be prioritised for the young and the elderly.
? 2019 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] Singapore; burden; generalized additive model; hospitalisation; influenza; pneumonia; tropics
PMID: 31433131 DOI: 10.1111/irv.12676
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[h=1]Estimates of influenza-associated hospitalisations in tropical Singapore, 2010-2017: Higher burden estimated in more recent years.[/h] Ng Y[SUP]1[/SUP], Chua LAV[SUP]1[/SUP], Ma S[SUP]1[/SUP], Jian Ming Lee V[SUP]2[/SUP].
[h=3]Author information[/h] 1 Epidemiology and Disease Control Division, Ministry of Health, Singapore City, Singapore. 2 Communicable Diseases Division, Ministry of Health, Singapore City, Singapore.
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] We previously estimated Singapore's influenza-associated hospitalisation rate for pneumonia and influenza (P&I) in 2010-2012 to be 29.6 per 100 000 person-years, which corresponds to 11.2% of all P&I hospitalisations.
[h=4]OBJECTIVES:[/h] This study aims to update Singapore's estimates of the influenza-associated pneumonia and influenza (P&I) hospitalisation burden using the latest data from 2010 to 2017.
[h=4]METHODS:[/h] We estimated the number of P&I hospitalisations associated with influenza using generalised additive models. We specified the weekly number of admissions for P&I and the weekly influenza positivity in the models, along with potential confounders such as weekly respiratory syncytial virus (RSV) positivity and meteorological data.
[h=4]RESULTS:[/h] In 2010-2017, 16.3% of all P&I hospitalisations in Singapore were estimated to be attributed to influenza, corresponding to an excess influenza-associated P&I hospitalisation rate of 50.1 per 100 000 person-years. Higher excess rates were estimated for children aged 0-4 years (186.8 per 100 000 person-years) and elderly aged ≥ 65 years (338.0 per 100 000 person-years). Higher influenza-associated hospitalisation rates were estimated for 2016 and 2017 (67.9 and 75.1 per 100 000 persons, respectively) years when the influenza A(H3N2) subtype was dominant.
[h=4]CONCLUSION:[/h] Influenza burden in Singapore has increased since 2010. Influenza vaccination programmes should continue to be prioritised for the young and the elderly.
? 2019 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] Singapore; burden; generalized additive model; hospitalisation; influenza; pneumonia; tropics
PMID: 31433131 DOI: 10.1111/irv.12676
Free full text