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Estimates of influenza and respiratory syncytial virus incidences with fraction modeling approach in Baguio City, the Philippines, 2012-2014

tetano

Editor, Senior Moderator
Influenza Other Respir Viruses. 2017 Apr 2. doi: 10.1111/irv.12453. [Epub ahead of print]
[h=1]Estimates of influenza and respiratory syncytial virus incidences with fraction modeling approach in Baguio City, the Philippines, 2012-2014.[/h] Kamigaki T[SUP]1[/SUP], Aldey PP[SUP]2[/SUP], Mercado ES[SUP]3[/SUP], Tan AG[SUP]2[/SUP], Javier JB[SUP]2[/SUP], Lupisan SP[SUP]4[/SUP], Oshitani H[SUP]1[/SUP], Tallo VL[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Estimation of the incidences of influenza and respiratory syncytial virus (RSV) infection is important for disease control. Previous estimate in the city showed a substantial burden of influenza in both outpatients and inpatients while it did not account for individuals who do not seek medical attention nor RSV.
[h=4]PATIENTS/METHODS:[/h] A total of 17,674 influenza like illness (ILI) and 13,242 severe acute respiratory illness (SARI) cases were recruited and samples were collected from 6,267 and 2,962 of ILI and SARI cases, respectively. RT-PCR assays were performed to detect influenza and RSV in the samples. A health-seeking behavior survey was conducted from February to April, 2014 to estimate the fraction of infected individuals who did not seek medical attention between rainy and dry season.
[h=4]RESULTS:[/h] Average influenza and RSV incidence rates in outpatients were 1.6 and 1.4 per 1,000 individuals, respectively, and the highest incidence rate for both viruses was found in the of 6-23 month age group. Average influenza and RSV hospitalization incidence rates were 1.7 and 1.9 per 1,000 individuals, respectively. Further, we estimated that the incidence rates of influenza and RSV in individuals who did not seek medical attention were 3-fold and 1.6-fold those in the medically attended population.
[h=4]CONCLUSIONS:[/h] RSV and influenza pose a substantial disease burden, particularly in hospitalized cases. The implementation of either a community-based approach or an enhanced surveillance system in combination with a community survey will allow a better understanding of the disease burdens of RSV and influenza in the Philippines. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.


[h=4]KEYWORDS:[/h] Health care seeking behaviour; incidence; influenza; respiratory syncytial virus

PMID: 28371393 DOI: 10.1111/irv.12453
 
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