Mary Wilson
Well-known member
September 2, 2021
doi:10.1001/jama.2021.15161
Jefferson M. Jones, MD, MPH[SUP]1[/SUP]; Mars Stone, PhD[SUP]2[/SUP]; Hasan Sulaeman, MS[SUP]2[/SUP]; et al
Key Points
Question Based on blood donations in the US from July 2020 through May 2021, how did infection- and vaccine-induced SARS-CoV-2 seroprevalence vary over time by demographic group and by geographic region?
Findings In this repeated cross-sectional study that included 1 443 519 blood donation specimens from a catchment area representing 74% of the US population, estimated SARS-CoV-2 seroprevalence weighted for differences between the study sample and general population increased from 3.5% in July 2020 to 20.2% for infection-induced antibodies and 83.3% for combined infection- and vaccine-induced antibodies in May 2021. Seroprevalence differed by age, race and ethnicity, and geographic region of residence, but these differences changed over the course of the study.
Meaning Based on a sample of blood donations in the US from July 2020 through May 2021, estimated SARS-CoV-2 seroprevalence increased over time and varied by age, race and ethnicity, and geographic region.
https://jamanetwork.com/journals/jama/fullarticle/2784013
doi:10.1001/jama.2021.15161
Jefferson M. Jones, MD, MPH[SUP]1[/SUP]; Mars Stone, PhD[SUP]2[/SUP]; Hasan Sulaeman, MS[SUP]2[/SUP]; et al
Key Points
Question Based on blood donations in the US from July 2020 through May 2021, how did infection- and vaccine-induced SARS-CoV-2 seroprevalence vary over time by demographic group and by geographic region?
Findings In this repeated cross-sectional study that included 1 443 519 blood donation specimens from a catchment area representing 74% of the US population, estimated SARS-CoV-2 seroprevalence weighted for differences between the study sample and general population increased from 3.5% in July 2020 to 20.2% for infection-induced antibodies and 83.3% for combined infection- and vaccine-induced antibodies in May 2021. Seroprevalence differed by age, race and ethnicity, and geographic region of residence, but these differences changed over the course of the study.
Meaning Based on a sample of blood donations in the US from July 2020 through May 2021, estimated SARS-CoV-2 seroprevalence increased over time and varied by age, race and ethnicity, and geographic region.
https://jamanetwork.com/journals/jama/fullarticle/2784013