tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2017 Sep 27. doi: 10.1111/irv.12495. [Epub ahead of print]
[h=1]Estimated rates of influenza-associated outpatient visits during 2001-2010 in six US integrated health care delivery organizations.[/h] Zhou H[SUP]1[/SUP], Thompson WW[SUP]1[/SUP], Belongia EA[SUP]2[/SUP], Fowlkes A[SUP]1[/SUP], Baxter R[SUP]3[/SUP], Jacobsen SJ[SUP]4[/SUP], Jackson ML[SUP]5[/SUP], Glanz JM[SUP]6[/SUP], Naleway AL[SUP]7[/SUP], Ford DC[SUP]1[/SUP], Weintraub E[SUP]1[/SUP], Shay DK[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Population-based estimates of influenza-associated outpatient visits including both pandemic and inter-pandemic seasons are uncommon. Comparisons of such estimates with laboratory-confirmed rates of outpatient influenza are rare.
[h=4]OBJECTIVE:[/h] To estimate influenza-associated outpatient visits in six US integrated health care delivery organizations enrolling ~7.7 million persons.
[h=4]METHODS:[/h] Using negative-binomial regression methods, we modeled rates of influenza-associated visits with ICD-9-CM-coded pneumonia or acute respiratory outpatient visits during 2001-10. These estimated counts were added to visits coded specifically for influenza to derive estimated rates. We compared these rates with those observed in two contemporaneous studies recording RT-PCR-confirmed influenza outpatient visits.
[h=4]RESULTS:[/h] Outpatient rates estimated with pneumonia visits were 39 (95% confidence interval [CI], 30-70) and 203 (95% CI, 180-240) per 10,000 person-years, respectively, for inter-pandemic and pandemic seasons. Corresponding rates estimated with respiratory visits were 185 (95% CI, 161-255) and 542 (95% CI, 441-823) per 10,000 person-years. During the pandemic, children aged 2-17 years had the largest increase in rates (when estimated with pneumonia visits, from 64 [95% CI, 50-121] to 381 [95% CI, 366-481]). Rates estimated with pneumonia visits were consistent with rates of RT-PCR-confirmed influenza visits during 4 of 5 seasons in one comparison study. In another, rates estimated with pneumonia visits during the pandemic for children and adults were consistent in timing, peak, and magnitude.
[h=4]CONCLUSIONS:[/h] Estimated rates of influenza-associated outpatient visits were higher in children than adults during pre-pandemic and pandemic seasons. Rates estimated with pneumonia visits plus influenza-coded visits were similar to rates from studies using RT-PCR-confirmed influenza. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] electronic health records; influenza, human; office visits; statistical models
PMID: 28960732 DOI: 10.1111/irv.12495
[h=1]Estimated rates of influenza-associated outpatient visits during 2001-2010 in six US integrated health care delivery organizations.[/h] Zhou H[SUP]1[/SUP], Thompson WW[SUP]1[/SUP], Belongia EA[SUP]2[/SUP], Fowlkes A[SUP]1[/SUP], Baxter R[SUP]3[/SUP], Jacobsen SJ[SUP]4[/SUP], Jackson ML[SUP]5[/SUP], Glanz JM[SUP]6[/SUP], Naleway AL[SUP]7[/SUP], Ford DC[SUP]1[/SUP], Weintraub E[SUP]1[/SUP], Shay DK[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Population-based estimates of influenza-associated outpatient visits including both pandemic and inter-pandemic seasons are uncommon. Comparisons of such estimates with laboratory-confirmed rates of outpatient influenza are rare.
[h=4]OBJECTIVE:[/h] To estimate influenza-associated outpatient visits in six US integrated health care delivery organizations enrolling ~7.7 million persons.
[h=4]METHODS:[/h] Using negative-binomial regression methods, we modeled rates of influenza-associated visits with ICD-9-CM-coded pneumonia or acute respiratory outpatient visits during 2001-10. These estimated counts were added to visits coded specifically for influenza to derive estimated rates. We compared these rates with those observed in two contemporaneous studies recording RT-PCR-confirmed influenza outpatient visits.
[h=4]RESULTS:[/h] Outpatient rates estimated with pneumonia visits were 39 (95% confidence interval [CI], 30-70) and 203 (95% CI, 180-240) per 10,000 person-years, respectively, for inter-pandemic and pandemic seasons. Corresponding rates estimated with respiratory visits were 185 (95% CI, 161-255) and 542 (95% CI, 441-823) per 10,000 person-years. During the pandemic, children aged 2-17 years had the largest increase in rates (when estimated with pneumonia visits, from 64 [95% CI, 50-121] to 381 [95% CI, 366-481]). Rates estimated with pneumonia visits were consistent with rates of RT-PCR-confirmed influenza visits during 4 of 5 seasons in one comparison study. In another, rates estimated with pneumonia visits during the pandemic for children and adults were consistent in timing, peak, and magnitude.
[h=4]CONCLUSIONS:[/h] Estimated rates of influenza-associated outpatient visits were higher in children than adults during pre-pandemic and pandemic seasons. Rates estimated with pneumonia visits plus influenza-coded visits were similar to rates from studies using RT-PCR-confirmed influenza. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] electronic health records; influenza, human; office visits; statistical models
PMID: 28960732 DOI: 10.1111/irv.12495