tetano
Editor, Senior Moderator
Epidemiol Infect. 2017 Sep 11:1-10. doi: 10.1017/S0950268817001972. [Epub ahead of print]
[h=1]Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes.[/h] Regan AK[SUP]1[/SUP], Moore HC[SUP]2[/SUP], Sullivan SG[SUP]3[/SUP], DE Klerk N[SUP]2[/SUP], Effler PV[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Seasonal influenza can cause significant morbidity in pregnant women. Much of the existing epidemiological evidence on influenza during pregnancy has focused on the 2009 A/H1N1 pandemic. To measure the epidemiological characteristics of seasonal influenza infection among pregnant women and the impact on infant health, a cohort of 86 779 pregnancies during the influenza season (2012-2014) was established using probabilistic linkage of notifiable infectious disease, hospital admission, and birth information. A total of 192 laboratory-confirmed influenza infections were identified (2?2 per 1000 pregnancies), 14?6% of which were admitted to hospital. There was no difference in the proportion of infections admitted to hospital by trimester or subtype of infection. Influenza B infections were more likely to occur in second trimester compared with influenza A/H3N2 and influenza A/H1N1 infections (41?3%, 23?6%, and 33?3%, respectively), and on average, infants born to women with influenza B during pregnancy had 4?0% (95% CI 0?3-7?6%) lower birth weight relative to optimal compared with infants born to uninfected women (P = 0?03). Results from this linked population-based study suggest that there are differences in maternal infection by virus type and subtype and support the provision of seasonal influenza vaccine to pregnant women.
[h=4]KEYWORDS:[/h] Epidemiology; infant health; influenza A virus; influenza B virus; pregnant women
PMID: 28891463 DOI: 10.1017/S0950268817001972
[h=1]Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes.[/h] Regan AK[SUP]1[/SUP], Moore HC[SUP]2[/SUP], Sullivan SG[SUP]3[/SUP], DE Klerk N[SUP]2[/SUP], Effler PV[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Seasonal influenza can cause significant morbidity in pregnant women. Much of the existing epidemiological evidence on influenza during pregnancy has focused on the 2009 A/H1N1 pandemic. To measure the epidemiological characteristics of seasonal influenza infection among pregnant women and the impact on infant health, a cohort of 86 779 pregnancies during the influenza season (2012-2014) was established using probabilistic linkage of notifiable infectious disease, hospital admission, and birth information. A total of 192 laboratory-confirmed influenza infections were identified (2?2 per 1000 pregnancies), 14?6% of which were admitted to hospital. There was no difference in the proportion of infections admitted to hospital by trimester or subtype of infection. Influenza B infections were more likely to occur in second trimester compared with influenza A/H3N2 and influenza A/H1N1 infections (41?3%, 23?6%, and 33?3%, respectively), and on average, infants born to women with influenza B during pregnancy had 4?0% (95% CI 0?3-7?6%) lower birth weight relative to optimal compared with infants born to uninfected women (P = 0?03). Results from this linked population-based study suggest that there are differences in maternal infection by virus type and subtype and support the provision of seasonal influenza vaccine to pregnant women.
[h=4]KEYWORDS:[/h] Epidemiology; infant health; influenza A virus; influenza B virus; pregnant women
PMID: 28891463 DOI: 10.1017/S0950268817001972