tetano
Editor, Senior Moderator
J Clin Virol. 2018 Feb 20;102:27-31. doi: 10.1016/j.jcv.2018.02.010. [Epub ahead of print]
[h=1]Epidemiology and seasonality of acute respiratory infections in hospitalized children over four consecutive years (2012-2016).[/h] Fillatre A[SUP]1[/SUP], Fran?ois C[SUP]2[/SUP], Segard C[SUP]1[/SUP], Duverlie G[SUP]2[/SUP], Hecquet D[SUP]1[/SUP], Pannier C[SUP]1[/SUP], Roussel C[SUP]1[/SUP], Zawadzki P[SUP]1[/SUP], Brochot E[SUP]2[/SUP], Castelain S[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Acute respiratory infections are a principal cause of illness and mortality especially in young children worldwide.
[h=4]OBJECTIVES:[/h] To study the epidemiology and seasonality of viral respiratory infections in hospitalized children (under the age of 16) between September 2012 and August 2016.
[h=4]STUDY DESIGN:[/h] Nasopharyngeal swabs or aspirates were collected from 3199 symptomatic patients and then screened with a routine multiplex PCR assay.
[h=4]RESULTS:[/h] Respiratory viruses were detected for 1624 (50.8%) of the 3199 children in the study population. Of these, 210 (13.3%) were positive for two viruses, 28 (1.7%) were positive for three, and 3 (0.2%) were positive for four. The viral profile varied with age. Some viruses were significantly more frequent in children under the age of 1 month (such as human respiratory syncytial virus (p < 0.0001)), whereas others were significantly more frequent in children over that age (such as influenza viruses (p < 0.0001) and adenoviruses (p = .0006)). The distribution of viruses is variable over the year depending on the species. However, the atmospheric temperature was rarely found to be a limiting factor in the circulation of respiratory viruses.
[h=4]CONCLUSIONS:[/h] our results constitute a detailed description of the distribution of respiratory viruses among hospitalized children over four consecutive years. Our data notably highlight the persistence of non-enveloped viruses and some enveloped viruses throughout the year-regardless of temperature variations.
Copyright ? 2018 Elsevier B.V. All rights reserved.
[h=4]KEYWORDS:[/h] Children; Coinfection; Epidemiology; Respiratory viruses; Seasons
PMID: 29477833 DOI: 10.1016/j.jcv.2018.02.010
[h=1]Epidemiology and seasonality of acute respiratory infections in hospitalized children over four consecutive years (2012-2016).[/h] Fillatre A[SUP]1[/SUP], Fran?ois C[SUP]2[/SUP], Segard C[SUP]1[/SUP], Duverlie G[SUP]2[/SUP], Hecquet D[SUP]1[/SUP], Pannier C[SUP]1[/SUP], Roussel C[SUP]1[/SUP], Zawadzki P[SUP]1[/SUP], Brochot E[SUP]2[/SUP], Castelain S[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Acute respiratory infections are a principal cause of illness and mortality especially in young children worldwide.
[h=4]OBJECTIVES:[/h] To study the epidemiology and seasonality of viral respiratory infections in hospitalized children (under the age of 16) between September 2012 and August 2016.
[h=4]STUDY DESIGN:[/h] Nasopharyngeal swabs or aspirates were collected from 3199 symptomatic patients and then screened with a routine multiplex PCR assay.
[h=4]RESULTS:[/h] Respiratory viruses were detected for 1624 (50.8%) of the 3199 children in the study population. Of these, 210 (13.3%) were positive for two viruses, 28 (1.7%) were positive for three, and 3 (0.2%) were positive for four. The viral profile varied with age. Some viruses were significantly more frequent in children under the age of 1 month (such as human respiratory syncytial virus (p < 0.0001)), whereas others were significantly more frequent in children over that age (such as influenza viruses (p < 0.0001) and adenoviruses (p = .0006)). The distribution of viruses is variable over the year depending on the species. However, the atmospheric temperature was rarely found to be a limiting factor in the circulation of respiratory viruses.
[h=4]CONCLUSIONS:[/h] our results constitute a detailed description of the distribution of respiratory viruses among hospitalized children over four consecutive years. Our data notably highlight the persistence of non-enveloped viruses and some enveloped viruses throughout the year-regardless of temperature variations.
Copyright ? 2018 Elsevier B.V. All rights reserved.
[h=4]KEYWORDS:[/h] Children; Coinfection; Epidemiology; Respiratory viruses; Seasons
PMID: 29477833 DOI: 10.1016/j.jcv.2018.02.010