tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2015 Aug;9 Suppl 1:3-12. doi: 10.1111/irv.12319.
[h=1]Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study.[/h] Caini S[SUP]1[/SUP], Huang QS[SUP]2[/SUP], Ciblak MA[SUP]3[/SUP], Kusznierz G[SUP]4[/SUP], Owen R[SUP]5[/SUP], Wangchuk S[SUP]6[/SUP], Henriques CM[SUP]7[/SUP], Njouom R[SUP]8[/SUP], Fasce RA[SUP]9[/SUP], Yu H[SUP]10[/SUP], Feng L[SUP]10[/SUP], Zambon M[SUP]11[/SUP], Clara AW[SUP]12[/SUP], Kosasih H[SUP]13[/SUP], Puzelli S[SUP]14[/SUP], Kadjo HA[SUP]15[/SUP], Emukule G[SUP]16[/SUP], Heraud JM[SUP]17[/SUP], Ang LW[SUP]18[/SUP], Venter M[SUP]19,[/SUP][SUP]20[/SUP], Mironenko A[SUP]21[/SUP], Brammer L[SUP]22[/SUP], Mai le TQ[SUP]23[/SUP], Schellevis F[SUP]1[/SUP], Plotkin S[SUP]24[/SUP], Paget J[SUP]1[/SUP]; Global Influenza B Study.
[h=3]Collaborators (31)[/h]
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000.
[h=4]METHODS:[/h] Twenty-six countries in the Southern (n = 5) and Northern (n = 7) hemispheres and intertropical belt (n = 14) provided virological and epidemiological data. We calculated the proportion of influenza cases due to type B and Victoria and Yamagata lineages in each country and season; tested the correlation between proportion of influenza B and maximum weekly influenza-like illness (ILI) rate during the same season; determined the frequency of vaccine mismatches; and described the age distribution of cases by virus type.
[h=4]RESULTS:[/h] The database included 935 673 influenza cases (2000-2013). Overall median proportion of influenza B was 22?6%, with no statistically significant differences across seasons. During seasons where influenza B was dominant or co-circulated (>20% of total detections), Victoria and Yamagata lineages predominated during 64% and 36% of seasons, respectively, and a vaccine mismatch was observed in ≈25% of seasons. Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres. Patients infected with influenza B were usually younger (5-17 years) than patients infected with influenza A.
[h=4]CONCLUSION:[/h] Influenza B is a common disease with some epidemiological differences from influenza A. This should be considered when optimizing control/prevention strategies in different regions and reducing the global burden of disease due to influenza.
? 2015 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] Burden of disease; Global Influenza B Study (GIBS); epidemiology; influenza; vaccination; vaccine mismatch
PMID: 26256290 [PubMed - in process]
[h=1]Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study.[/h] Caini S[SUP]1[/SUP], Huang QS[SUP]2[/SUP], Ciblak MA[SUP]3[/SUP], Kusznierz G[SUP]4[/SUP], Owen R[SUP]5[/SUP], Wangchuk S[SUP]6[/SUP], Henriques CM[SUP]7[/SUP], Njouom R[SUP]8[/SUP], Fasce RA[SUP]9[/SUP], Yu H[SUP]10[/SUP], Feng L[SUP]10[/SUP], Zambon M[SUP]11[/SUP], Clara AW[SUP]12[/SUP], Kosasih H[SUP]13[/SUP], Puzelli S[SUP]14[/SUP], Kadjo HA[SUP]15[/SUP], Emukule G[SUP]16[/SUP], Heraud JM[SUP]17[/SUP], Ang LW[SUP]18[/SUP], Venter M[SUP]19,[/SUP][SUP]20[/SUP], Mironenko A[SUP]21[/SUP], Brammer L[SUP]22[/SUP], Mai le TQ[SUP]23[/SUP], Schellevis F[SUP]1[/SUP], Plotkin S[SUP]24[/SUP], Paget J[SUP]1[/SUP]; Global Influenza B Study.
[h=3]Collaborators (31)[/h]
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000.
[h=4]METHODS:[/h] Twenty-six countries in the Southern (n = 5) and Northern (n = 7) hemispheres and intertropical belt (n = 14) provided virological and epidemiological data. We calculated the proportion of influenza cases due to type B and Victoria and Yamagata lineages in each country and season; tested the correlation between proportion of influenza B and maximum weekly influenza-like illness (ILI) rate during the same season; determined the frequency of vaccine mismatches; and described the age distribution of cases by virus type.
[h=4]RESULTS:[/h] The database included 935 673 influenza cases (2000-2013). Overall median proportion of influenza B was 22?6%, with no statistically significant differences across seasons. During seasons where influenza B was dominant or co-circulated (>20% of total detections), Victoria and Yamagata lineages predominated during 64% and 36% of seasons, respectively, and a vaccine mismatch was observed in ≈25% of seasons. Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres. Patients infected with influenza B were usually younger (5-17 years) than patients infected with influenza A.
[h=4]CONCLUSION:[/h] Influenza B is a common disease with some epidemiological differences from influenza A. This should be considered when optimizing control/prevention strategies in different regions and reducing the global burden of disease due to influenza.
? 2015 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] Burden of disease; Global Influenza B Study (GIBS); epidemiology; influenza; vaccination; vaccine mismatch
PMID: 26256290 [PubMed - in process]