tetano
Editor, Senior Moderator
Epidemiol Infect. 2012 Aug 1:1-10. [Epub ahead of print]
Epidemiological analysis of critically ill adult patients with pandemic influenza A(H1N1) in South Korea.
Hong SB, Choi EY, Kim SH, Suh GY, Park MS, Lee MG, Lim J, Lee HK, Kim SC, Kim SJ, Kim KU, Kwak SH, Koh Y.
Source
Ulsan University College of Medicine, Seoul, Korea.
Abstract
SUMMARY A total of 245 patients with confirmed 2009 H1N1 influenza were admitted to the intensive-care units of 28 hospitals (South Korea). Their mean age was 55?3 years with 68?6% aged >50 years, and 54?7% male. Nine were obese and three were pregnant. One or more comorbidities were present in 83?7%, and nosocomial acquisition occurred in 14?3%. In total, 107 (43?7%) patients received corticosteroids and 66?1% required mechanical ventilation. Eighty (32?7%) patients died within 30 days after onset of symptoms and 99 (40?4%) within 90 days. Multivariate logistic regression analysis showed that the clinician's decision to prescribe corticosteroids, older age, Sequential Organ Failure Assessment score and nosocomial bacterial pneumonia were independent risk factors for 90-day mortality. In contrast with Western countries, critical illness in Korea in relation to 2009 H1N1 was most common in older patients with chronic comorbidities; nosocomial acquisition occurred occasionally but disease in obese or pregnant patients was uncommon.
PMID:
22853817
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22853817
Epidemiological analysis of critically ill adult patients with pandemic influenza A(H1N1) in South Korea.
Hong SB, Choi EY, Kim SH, Suh GY, Park MS, Lee MG, Lim J, Lee HK, Kim SC, Kim SJ, Kim KU, Kwak SH, Koh Y.
Source
Ulsan University College of Medicine, Seoul, Korea.
Abstract
SUMMARY A total of 245 patients with confirmed 2009 H1N1 influenza were admitted to the intensive-care units of 28 hospitals (South Korea). Their mean age was 55?3 years with 68?6% aged >50 years, and 54?7% male. Nine were obese and three were pregnant. One or more comorbidities were present in 83?7%, and nosocomial acquisition occurred in 14?3%. In total, 107 (43?7%) patients received corticosteroids and 66?1% required mechanical ventilation. Eighty (32?7%) patients died within 30 days after onset of symptoms and 99 (40?4%) within 90 days. Multivariate logistic regression analysis showed that the clinician's decision to prescribe corticosteroids, older age, Sequential Organ Failure Assessment score and nosocomial bacterial pneumonia were independent risk factors for 90-day mortality. In contrast with Western countries, critical illness in Korea in relation to 2009 H1N1 was most common in older patients with chronic comorbidities; nosocomial acquisition occurred occasionally but disease in obese or pregnant patients was uncommon.
PMID:
22853817
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22853817