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Epidemiologic and clinical parameters in hospitalized patients with novel Influenza A (H1N1) in Taranto province, Italy

tetano

Editor, Senior Moderator
Infez Med. 2010 Jun 1;18(2):104-107.
[Epidemiologic and clinical parameters in hospitalized patients with novel Influenza A (H1N1) in Taranto province, Italy.]

[Article in Italian]

Buccoliero G, Romanelli C, Lonero G, Loperfido P, Chimienti A, Resta F.

S.C. Malattie Infettive, Presidio Ospedaliero Centrale, Stabilimento San G. Moscati, AUSL Taranto, Italy.
Abstract

The global spread of novel influenza A (H1N1) led the World Health Organization to declare a pandemic on June 11, 2009. Our study aimed to describe the epidemiologic and clinical parameters of hospitalized patients during the pandemic. Fifty-one persons with suspected influenza A H1N1 were hospitalized. Thirty-two of them (14 male and 18 female) were positive for novel influenza A (H1N1) viral RNA by real time PCR in nasopharyngeal specimens. Of those who tested positive, 46.8% (15 patients) were aged between 25-49 years and only 9.3% (3) were over 65 years old. Nineteen of the 32 presented a co-morbidity. The mean duration of hospitalization was 6.5 days (range 3-19). An influenza complication was presented by 68.7% of patients (all of them older than 65 years), which in most cases was pulmonary disease (18 bronchopneumonia, 2 interstitial pneumonia). Four patients required mechanical ventilation in Intensive Therapy Care. One patient died of a concomitant myopericarditis. Of the patients with influenza complications, 60% presented co-morbidity conditions. Neurologic complication (encephalitis) occurred in two young women; prognosis was good and without neurologic sequelae. In conclusion, our data do not show a correlation between gender and risk of hospitalization or influenza complication. The presence of co-morbidity does not increase the risk of pulmonary complication, which is more frequent among young adults.

PMID: 20610932 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/20610932
 
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