tetano
Editor, Senior Moderator
Epidemiol Infect
. 2025 Mar 24:153:e49.
doi: 10.1017/S0950268824001559. Global patterns and trends in deaths of influenza-associated lower respiratory infections from 1990 to 2019
Can Chen[SUP] 1 [/SUP], Dingmo Chen[SUP] 1 2 [/SUP], Yuxia Du[SUP] 1 [/SUP], Daixi Jiang[SUP] 1 [/SUP], Kexin Cao[SUP] 1 [/SUP], Mengya Yang[SUP] 1 [/SUP], Xiaoyue Wu[SUP] 1 [/SUP], Mengsha Chen[SUP] 1 [/SUP], Wenkai Zhou[SUP] 1 [/SUP], Jiaxing Qi[SUP] 1 [/SUP], Yue You[SUP] 1 [/SUP], Rui Yan[SUP] 1 [/SUP], Shigui Yang[SUP] 1 [/SUP]; RIDPHE Group
Affiliations
This study examined global trends in influenza-associated lower respiratory infections (LRIs) deaths from 1990 to 2019 using data from the GBD 2019. The annual percentage change (APC) and average annual percentage change (AAPC) were used to analyze age-standardized death rates (ASDR). Globally, the ASDR of influenza-associated LRIs was 3.29/100,000 in 2019, which was higher in the African region (6.57/100,000) and among adults aged 70 years and older (29.88/100,000). The ASDR of influenza-associated LRIs decreased significantly from 1990 to 2019 (AAPC = -1.88%, P < 0.05). However, it was significantly increased among adults aged 70 years and older during 2017-2019 (APC = 2.31%, P < 0.05), especially in Western Pacific Region and South-East Asia Regions. The ratio of death rates between adults aged 70 years and older and children aged under 5 years increased globally from 1.63 in 1990 to 5.34 in 2019, and the Western Pacific Region experienced the most substantial increase, with the ratio soaring from 1.83 in 1990 to 12.98 in 2019. Despite a decline in the global ASDR of influenza-associated LRIs, it continues to impose a significant burden, particularly in the African, Western Pacific regions and among the elderly population.
Keywords: Western Pacific region; adults aged 70 years and older; influenza; lower respiratory infections; trends.
. 2025 Mar 24:153:e49.
doi: 10.1017/S0950268824001559. Global patterns and trends in deaths of influenza-associated lower respiratory infections from 1990 to 2019
Can Chen[SUP] 1 [/SUP], Dingmo Chen[SUP] 1 2 [/SUP], Yuxia Du[SUP] 1 [/SUP], Daixi Jiang[SUP] 1 [/SUP], Kexin Cao[SUP] 1 [/SUP], Mengya Yang[SUP] 1 [/SUP], Xiaoyue Wu[SUP] 1 [/SUP], Mengsha Chen[SUP] 1 [/SUP], Wenkai Zhou[SUP] 1 [/SUP], Jiaxing Qi[SUP] 1 [/SUP], Yue You[SUP] 1 [/SUP], Rui Yan[SUP] 1 [/SUP], Shigui Yang[SUP] 1 [/SUP]; RIDPHE Group
Affiliations
- PMID: 40123429
- DOI: 10.1017/S0950268824001559
This study examined global trends in influenza-associated lower respiratory infections (LRIs) deaths from 1990 to 2019 using data from the GBD 2019. The annual percentage change (APC) and average annual percentage change (AAPC) were used to analyze age-standardized death rates (ASDR). Globally, the ASDR of influenza-associated LRIs was 3.29/100,000 in 2019, which was higher in the African region (6.57/100,000) and among adults aged 70 years and older (29.88/100,000). The ASDR of influenza-associated LRIs decreased significantly from 1990 to 2019 (AAPC = -1.88%, P < 0.05). However, it was significantly increased among adults aged 70 years and older during 2017-2019 (APC = 2.31%, P < 0.05), especially in Western Pacific Region and South-East Asia Regions. The ratio of death rates between adults aged 70 years and older and children aged under 5 years increased globally from 1.63 in 1990 to 5.34 in 2019, and the Western Pacific Region experienced the most substantial increase, with the ratio soaring from 1.83 in 1990 to 12.98 in 2019. Despite a decline in the global ASDR of influenza-associated LRIs, it continues to impose a significant burden, particularly in the African, Western Pacific regions and among the elderly population.
Keywords: Western Pacific region; adults aged 70 years and older; influenza; lower respiratory infections; trends.