tetano
Editor, Senior Moderator
Appl Environ Microbiol. 2016 Apr 15. pii: AEM.00133-16. [Epub ahead of print]
[h=1]Environmental Stability of Swine and Human Pandemic Influenza Viruses in Water Under Variable Conditions of Temperature, Salinity, and pH.[/h] Poulson RL[SUP]1[/SUP], Tompkins SM[SUP]2[/SUP], Berghaus RD[SUP]3[/SUP], Brown JD[SUP]3[/SUP], Stallknecht DE[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] The movement of influenza A viruses (IAV) from wild bird reservoirs to domestic animals and humans is well established, but the transmission mechanisms that facilitate efficient movement across and within these host populations are not fully defined. Although predominant routes of transmission vary between host populations, the extent of IAV environmental stability needed for efficient transmission also may vary. Because of this, we hypothesized that viral stability would differ in response to varied host-related transmission mechanisms; if correct, such phenotypic variation could represent a potential marker for the emergence of novel animal or human influenza viruses. Here, the objective was to evaluate the ability of eight swine and six human IAV isolates to remain infective under various pH, temperature, and salinity conditions using a pre-established distilled water system. Swine and human viruses persisted longest at near-neutral pH, cold temperatures, or under "fresh water" conditions. Additionally, no significant differences in persistence were observed between pandemic and non-pandemic IAV. Our results indicate that there have been no apparent changes in the environmental stability of the viruses related to host adaptation.
[h=4]IMPORTANCE:[/h] This study assesses the environmental stability of eight swine and six human IAV, including viruses associated with the 2009 H1N1 pandemic, in a distilled water system. The important findings of this work are that 1) IAV persistence can be affected by environmental variables and 2) no marked changes were noted between human/swine IAV nor between pandemic/non-pandemic IAV.
Copyright ? 2016, American Society for Microbiology. All Rights Reserved.
PMID: 27084011 [PubMed - as supplied by publisher]
[h=1]Environmental Stability of Swine and Human Pandemic Influenza Viruses in Water Under Variable Conditions of Temperature, Salinity, and pH.[/h] Poulson RL[SUP]1[/SUP], Tompkins SM[SUP]2[/SUP], Berghaus RD[SUP]3[/SUP], Brown JD[SUP]3[/SUP], Stallknecht DE[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] The movement of influenza A viruses (IAV) from wild bird reservoirs to domestic animals and humans is well established, but the transmission mechanisms that facilitate efficient movement across and within these host populations are not fully defined. Although predominant routes of transmission vary between host populations, the extent of IAV environmental stability needed for efficient transmission also may vary. Because of this, we hypothesized that viral stability would differ in response to varied host-related transmission mechanisms; if correct, such phenotypic variation could represent a potential marker for the emergence of novel animal or human influenza viruses. Here, the objective was to evaluate the ability of eight swine and six human IAV isolates to remain infective under various pH, temperature, and salinity conditions using a pre-established distilled water system. Swine and human viruses persisted longest at near-neutral pH, cold temperatures, or under "fresh water" conditions. Additionally, no significant differences in persistence were observed between pandemic and non-pandemic IAV. Our results indicate that there have been no apparent changes in the environmental stability of the viruses related to host adaptation.
[h=4]IMPORTANCE:[/h] This study assesses the environmental stability of eight swine and six human IAV, including viruses associated with the 2009 H1N1 pandemic, in a distilled water system. The important findings of this work are that 1) IAV persistence can be affected by environmental variables and 2) no marked changes were noted between human/swine IAV nor between pandemic/non-pandemic IAV.
Copyright ? 2016, American Society for Microbiology. All Rights Reserved.
PMID: 27084011 [PubMed - as supplied by publisher]