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England: 2022 mpox cases

Research and analysis

Monkeypox outbreak: epidemiological overview, 11 October 2022


Updated 11 October 2022

Contents
  1. Current epidemiological situation as of 10 October 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 10 October 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 10 October 2022 there were 3,523 confirmed and 150 highly probable monkeypox cases detected in the UK: 3,673 in total. Of these, 94 were in Scotland, 34 were in Northern Ireland, 46 were in Wales and 3,499 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 10 October 2022
England3,499 (+19)3,349 (+19)150
Northern Ireland34340
Scotland94940
Wales46460
Total3,673 (+19)3,523 (+19)150
*The numbers in brackets show change since last report (3 October 2022)

A high proportion of England cases were London residents (69%, 2,411 of 3,486 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,598 (98.6%) were men and 51 were women. The median age of confirmed and highly probable cases in the UK was 37 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 10 October 2022
East of England117+1
East Midlands65+1
London2,411+14
North East480
North West2230
South East322+2
South West910
West Midlands1260
Yorkshire and Humber83+1
Under investigation**130
Total3,499+19
**Address not yet confirmed. Negative changes due to updates to location information.


...
https://www.gov.uk/government/publi...reak-epidemiological-overview-11-october-2022
 
Research and analysis

Monkeypox outbreak: epidemiological overview, 18 October 2022


Updated 18 October 2022

Contents
  1. Current epidemiological situation as of 17 October 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 17 October 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 17 October 2022 there were 3,537 confirmed and 149 highly probable monkeypox cases detected in the UK: 3,686 in total. Of these, 94 were in Scotland, 34 were in Northern Ireland, 46 were in Wales and 3,512 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 17 October 2022
England3,512 (+13)3,363 (+14)149 (-1)
Northern Ireland34340
Scotland94940
Wales46460
3,686 (+13)3,537 (+14)149 (-1)
*The numbers in brackets show change since last report (10 October 2022)

A high proportion of England cases were London residents (69%, 2,415 of 3,499 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,613 (98.6%) were men and 51 were women. The median age of confirmed and highly probable cases in the UK was 36 years (interquartile range 30-44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 17 October 2022
East of England120+3
East Midlands66+1
London2,415+4
North East480
North West226+3
South East323+1
South West92+1
West Midlands127+1
Yorkshire and Humber82-1
Under investigation**130
3,512+13
**Address not yet confirmed. Negative changes due to updates to location information.

...

https://www.gov.uk/government/publi...reak-epidemiological-overview-18-october-2022
 
Research and analysis

Monkeypox outbreak: epidemiological overview, 25 October 2022


Updated 25 October 2022

Contents
  1. Current epidemiological situation as of 24 October 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Data as of 24 October 2022

Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 24 October 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 24 October 2022 there were 3,548 confirmed and 150 highly probable monkeypox cases detected in the UK: 3,698 in total. Of these, 94 were in Scotland, 34 were in Northern Ireland, 46 were in Wales and 3,524 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 24 October 2022
England3,524 (+12)3,374 (+11)150 (+1)
Northern Ireland34340
Scotland94940
Wales46460
Total3,698 (+12)3,548 (+11)150 (+1)
*The numbers in brackets show change since last report (17 October 2022)

A high proportion of England cases were London residents (69%, 2,423 of 3,511 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,625 (98.6%) were men and 51 were women. The median age of confirmed and highly probable cases in the UK was 36 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 24 October 2022
East of England122+2
East Midlands660
London2,423+8
North East480
North West2260
South East324+1
South West920
West Midlands1270
Yorkshire and Humber83+1
Under investigation**130
Total3,524+12
**Address not yet confirmed. Negative changes due to updates to location information.

...

https://www.gov.uk/government/publi...reak-epidemiological-overview-25-october-2022
 
Research and analysis

Monkeypox outbreak: epidemiological overview, 1 November 2022


Updated 1 November 2022

Contents
  1. Current epidemiological situation as of 31 October 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Data as of 31 October 2022

Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 31 October 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 31 October 2022 there were 3,552 confirmed and 149 highly probable monkeypox cases detected in the UK: 3,701 in total. Of these, 94 were in Scotland, 34 were in Northern Ireland, 46 were in Wales and 3,527 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 31 October 2022
England3,527 (+3)3,378 (+4)149 (–1)
Northern Ireland34340
Scotland94940
Wales46460
Total3,701 (+3)3,552 (+4)149 (–1)
*The numbers in brackets show change since last report (24 October 2022)

A high proportion of England cases were London residents (69%, 2,424 of 3,514 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,628 (98.6%) were men and 51 were women. The median age of confirmed and highly probable cases in the UK was 37 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 31 October 2022
East of England1220
East Midlands660
London2,424+1
North East480
North West227+1
South East3240
South West920
West Midlands1270
Yorkshire and Humber84+1
Under investigation**130
Total3,527+3
**Address not yet confirmed. Negative changes due to updates to location information.

...

https://www.gov.uk/government/publi...reak-epidemiological-overview-1-november-2022
 
Research and analysis

Monkeypox outbreak: epidemiological overview, 8 November 2022


Updated 8 November 2022

Contents
  1. Current epidemiological situation as of 7 November 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Data as of 7 November 2022

Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 7 November 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 7 November 2022, there were 3,554 confirmed and 149 highly probable monkeypox cases detected in the UK: 3,703 in total. Of these, 94 were in Scotland, 34 were in Northern Ireland, 47 were in Wales and 3,528 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 7 November 2022
England3,528 (+1)3,379 (+1)149
Northern Ireland34340
Scotland94940
Wales47 (+1)47 (+1)0
Total3,703 (+2)3,554 (+2)149
*The numbers in brackets show change since last report (31 October 2022)

A high proportion of England cases were London residents (69%, 2,424 of 3,515 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,629 (98.6%) were men and 51 were women. The median age of confirmed and highly probable cases in the UK was 37 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 7 November 2022
East of England1220
East Midlands660
London2,4240
North East480
North West2270
South East3240
South West920
West Midlands128+1
Yorkshire and Humber840
Under investigation**130
Total3,528+1
**Address not yet confirmed. Negative changes due to updates to location information.


...
https://www.gov.uk/government/publi...reak-epidemiological-overview-8-november-2022
 
Research and analysis

Monkeypox outbreak: epidemiological overview, 15 November 2022


Updated 15 November 2022

Contents
  1. Current epidemiological situation as of 14 November 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Data as of 14 November 2022

Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 14 November 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 14 November 2022, there were 3,561 confirmed and 149 highly probable monkeypox cases detected in the UK: 3,710 in total. Of these, 95 were in Scotland, 34 were in Northern Ireland, 47 were in Wales and 3,534 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 14 November 2022
England3,534 (+6)3,385 (+6)149
Northern Ireland34340
Scotland95 (+1)95 (+1)0
Wales47470
3,710 (+7)3,561 (+7)149
*The numbers in brackets show change since last report (7 November 2022).

A high proportion of England cases were London residents (69%, 2,428 of 3,521 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,635 (98.6%) were men and 52 were women. The median age of confirmed and highly probable cases in the UK was 37 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 14 November 2022
East of England1220
East Midlands660
London2,428+4
North East480
North West2270
South East325+1
South West920
West Midlands129+1
Yorkshire and Humber840
Under investigation**130
3,534+6
**Address not yet confirmed. Negative changes due to updates to location information.

...
https://www.gov.uk/government/publi...eak-epidemiological-overview-15-november-2022
 
Research and analysis

Monkeypox outbreak: epidemiological overview, 22 November 2022


Updated 22 November 2022

Contents
  1. Current epidemiological situation as of 21 November 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 21 November 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 21 November 2022 there were 3,570 confirmed and 150 highly probable monkeypox cases detected in the UK; 3,720 in total. Of these, 96 were in Scotland, 34 were in Northern Ireland, 47 were in Wales and 3,543 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 21 November 2022
England3,543 (+9)3,393 (+8)150 (+1)
Northern Ireland34340
Scotland96 (+1)96 (+1)0
Wales47470
3,720 (+10)3,570 (+9)150 (+1)
*The numbers in brackets show change since last report (14 November 2022)

A high proportion of England cases were London residents (69%, 2,431 of 3,530 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,645 (98.6%) were men and 52 were women. The median age of confirmed and highly probable cases in the UK was 37 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 21 November 2022
East of England1220
East Midlands660
London2,431+3
North East480
North West229+2
South East326+1
South West93+1
West Midlands131+2
Yorkshire and Humber840
Under investigation**130
3,543+9
**Address not yet confirmed. Negative changes due to updates to location information.

...

https://www.gov.uk/government/publi...eak-epidemiological-overview-22-november-2022
 
Research and analysis

Monkeypox outbreak: epidemiological overview, 29 November 2022


Updated 29 November 2022

Contents
  1. Current epidemiological situation as of 28 November 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Data as of 28 November 2022

Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 28 November 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 28 November 2022 there were 3,575 confirmed and 150 highly probable monkeypox cases detected in the UK; 3,725 in total. Of these, 97 were in Scotland, 34 were in Northern Ireland, 47 were in Wales and 3,547 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 28 November 2022
England3,547 (+4)3,397 (+4)150
Northern Ireland34340
Scotland97 (+1)97 (+1)0
Wales47470
3,725 (+5)3,575 (+5)150
*The numbers in brackets show change since last report (21 November 2022).

A high proportion of England cases were London residents (69%, 2,434 of 3,534 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,650 (98.6%) were men and 52 were women. The median age of confirmed and highly probable cases in the UK was 37 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 28 November 2022
East of England1220
East Midlands660
London2,434+3
North East49+1
North West2290
South East3260
South West930
West Midlands1310
Yorkshire and Humber840
Under investigation**130
3,547+4
**Address not yet confirmed. Negative changes due to updates to location information.

...
https://www.gov.uk/government/publi...eak-epidemiological-overview-29-november-2022
 
Research and analysis

Monkeypox outbreak: epidemiological overview, 6 December 2022


Updated 6 December 2022

Contents
  1. Current epidemiological situation as of 5 December 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Data as of 5 December 2022

This epidemiological overview and the accompanying spreadsheet of counts of monkeypox by region and upper tier local authority will be published for the last time on 20 December 2022, due to low case numbers and availability of alternative reports.

As monkeypox continues to be a notifiable infection, please refer to the UK Health Security Agency (UKHSA) notifications of infectious diseases reports for weekly updates (but not cumulative totals) on laboratory-notified monkeypox cases in England and on notifications of clinically suspected monkeypox in England and Wales by region and local authority. Further technical briefings will provide more detailed epidemiological analyses.

Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 5 December 2022


Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes monkeypox). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 5 December 2022 there were 3,580 confirmed and 150 highly probable monkeypox cases detected in the UK: 3,730 in total. Of these, 97 were in Scotland, 34 were in Northern Ireland, 47 were in Wales and 3,552 were in England.

Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 5 December 2022
England3,552 (+5)3,402 (+5)150
Northern Ireland34340
Scotland97970
Wales47470
Total3,730 (+5)3,580 (+5)150
*The numbers in brackets show change since last report (28 November 2022).

A high proportion of England cases were London residents (69%, 2,435 of 3,539 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,654 (98.6%) were men and 53 were women. The median age of confirmed and highly probable cases in the UK was 36 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 5 December 2022
East of England1220
East Midlands660
London2,435+1
North East50+1
North West232+3
South East3260
South West930
West Midlands1310
Yorkshire and Humber840
Under investigation**130
Total3,552+5
**Address not yet confirmed. Negative changes due to updates to location information.

...

https://www.gov.uk/government/publi...reak-epidemiological-overview-6-december-2022
 
Research and analysis

Mpox (monkeypox) outbreak: epidemiological overview, 20 December 2022


Updated 20 December 2022

Contents
  1. Current epidemiological situation as of 19 December 2022
  2. Data sources
  3. Information about this publication
  4. Additional resources
Data as of 19 December 2022

This epidemiological overview and the accompanying spreadsheet of counts of monkeypox (mpox) by region and upper tier local authoritywill be published for the last time on 20 December 2022, due to low case numbers and availability of alternative reports.

As mpox continues to be a notifiable infection, please refer to the UK Health Security Agency (UKHSA) notifications of infectious diseases reports for weekly updates (but not cumulative totals) on laboratory-notified mpox cases in England and on notifications of clinically suspected mpox in England and Wales by region and local authority. Further technical briefings will provide more detailed epidemiological analyses.

Mpox is a zoonotic infection, caused by the mpox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where mpox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of mpox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and one was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 19 December 2022


Cases of mpox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the mpox technical briefing.

To expand the UK’s capability to detect mpox cases, some NHS laboratories are now testing suspected mpox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which includes mpox). Since 25 July 2022, the mpox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a mpox PCR test as confirmed cases. The counts below combine both of these categories.

Up to 19 December 2022 there were 3,582 confirmed and 148 highly probable mpox cases detected in the UK: 3,730 in total. Of these, 97 were in Scotland, 34 were in Northern Ireland, 47 were in Wales and 3,552 were in England. There were no new cases of mpox in this update compared with 7 days prior.

Table 1: Number of confirmed and highly probable mpox cases by UK nation of residence, 6 May to 19 December 2022
England3,5523,404148
Northern Ireland34340
Scotland97970
Wales47470
Total3,7303,582148
*The numbers in brackets show change since last report (12 December 2022)

A high proportion of England cases were London residents (69%, 2,435 of 3,539 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,653 (98.6%) were men and 53 were women. The median age of confirmed and highly probable cases in the UK was 36 years (interquartile range 30 to 44).

Table 2: Number of confirmed and highly probable mpox cases by region of residence, England, 6 May to 19 December 2022
East of England1230
East Midlands660
London2,4350
North East500
North West2310
South East3260
South West930
West Midlands1310
Yorkshire and Humber840
Under investigation**130
Total3,5520
**Address not yet confirmed. Negative changes due to updates to location information.

...
https://www.gov.uk/government/public...-december-2022
 
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