tetano
Editor, Senior Moderator
Endocr Res
. 2021 Feb 26;1-2.
doi: 10.1080/07435800.2021.1892748. Online ahead of print.
Insulin Treatment May Not Be Associated with Increased Mortality in Patients with COVID-19 and Concurrent Diabetes
Chia Siang Kow[SUP] 1 [/SUP], Syed Shahzad Hasan[SUP] 2 3 [/SUP]
Affiliations
Abstract
Previous study reported that preadmission insulin treatment in patients with coronavirus disease 2019 (COVID-19) and concurrent diabetes was associated with a significantly increased odds of mortality. However, such association may be modified by possible baseline differences in glycemic control between insulin users and non-insulin users. Misinterpretation of the association between insulin treatment and mortality could lead to confusion in clinical practice and hospitalized patients with COVID-19 for whom insulin treatment is appropriately indicated may be omitted from such treatment. However, requirement for insulin during hospitalization for COVID-19 may be a marker of poor prognosis and as such could be used to identify patient population who require more aggressive treatments to prevent mortality.
Keywords: COVID-19; HbA1c; diabetes; insulin; mortality.
. 2021 Feb 26;1-2.
doi: 10.1080/07435800.2021.1892748. Online ahead of print.
Insulin Treatment May Not Be Associated with Increased Mortality in Patients with COVID-19 and Concurrent Diabetes
Chia Siang Kow[SUP] 1 [/SUP], Syed Shahzad Hasan[SUP] 2 3 [/SUP]
Affiliations
- PMID: 33635726
- DOI: 10.1080/07435800.2021.1892748
Abstract
Previous study reported that preadmission insulin treatment in patients with coronavirus disease 2019 (COVID-19) and concurrent diabetes was associated with a significantly increased odds of mortality. However, such association may be modified by possible baseline differences in glycemic control between insulin users and non-insulin users. Misinterpretation of the association between insulin treatment and mortality could lead to confusion in clinical practice and hospitalized patients with COVID-19 for whom insulin treatment is appropriately indicated may be omitted from such treatment. However, requirement for insulin during hospitalization for COVID-19 may be a marker of poor prognosis and as such could be used to identify patient population who require more aggressive treatments to prevent mortality.
Keywords: COVID-19; HbA1c; diabetes; insulin; mortality.