tetano
Editor, Senior Moderator
Vet Microbiol. 2018 Feb;214:1-6. doi: 10.1016/j.vetmic.2017.11.033. Epub 2017 Nov 27.
[h=1]Emergence of H3N8 equine influenza virus in donkeys in China in 2017.[/h] Yang H[SUP]1[/SUP], Xiao Y[SUP]2[/SUP], Meng F[SUP]1[/SUP], Sun F[SUP]2[/SUP], Chen M[SUP]2[/SUP], Cheng Z[SUP]2[/SUP], Chen Y[SUP]1[/SUP], Liu S[SUP]2[/SUP], Chen H[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Equine influenza virus is a major respiratory pathogen in horses. Although both horses and donkeys belong to the genus Equus, donkey infection with influenza viruses is rare. In March 2017, an influenza outbreak occurred in donkeys in Shandong province, China. The causative virus, A/donkey/Shandong/1/2017(H3N8), was isolated from a dead donkey. Genetic analysis indicated that the virus originated from influenza A (H3N8) clade 2 of the Florida sub-lineage that has been circulating in Asian equine populations. Comparison of the deduced amino acid sequence of the HA gene of this causative virus with that of the A/equine/Richmond/1/2007 vaccine strain showed that substitutions had occurred in the antigenic regions A, B, and C. This study provides insight into the currently circulating and newly emerging H3N8 strains in donkeys in China.
[h=4]KEYWORDS:[/h] Donkey; Equine influenza virus; H3N8 subtype; Phylogenetic analyses
PMID: 29408020 DOI: 10.1016/j.vetmic.2017.11.033
[h=1]Emergence of H3N8 equine influenza virus in donkeys in China in 2017.[/h] Yang H[SUP]1[/SUP], Xiao Y[SUP]2[/SUP], Meng F[SUP]1[/SUP], Sun F[SUP]2[/SUP], Chen M[SUP]2[/SUP], Cheng Z[SUP]2[/SUP], Chen Y[SUP]1[/SUP], Liu S[SUP]2[/SUP], Chen H[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Equine influenza virus is a major respiratory pathogen in horses. Although both horses and donkeys belong to the genus Equus, donkey infection with influenza viruses is rare. In March 2017, an influenza outbreak occurred in donkeys in Shandong province, China. The causative virus, A/donkey/Shandong/1/2017(H3N8), was isolated from a dead donkey. Genetic analysis indicated that the virus originated from influenza A (H3N8) clade 2 of the Florida sub-lineage that has been circulating in Asian equine populations. Comparison of the deduced amino acid sequence of the HA gene of this causative virus with that of the A/equine/Richmond/1/2007 vaccine strain showed that substitutions had occurred in the antigenic regions A, B, and C. This study provides insight into the currently circulating and newly emerging H3N8 strains in donkeys in China.
[h=4]KEYWORDS:[/h] Donkey; Equine influenza virus; H3N8 subtype; Phylogenetic analyses
PMID: 29408020 DOI: 10.1016/j.vetmic.2017.11.033