tetano
Editor, Senior Moderator
Influenza Other Respi Viruses. 2011 Aug 4. doi: 10.1111/j.1750-2659.2011.00274.x. [Epub ahead of print]
Emergence of 2009A/H1N1 cases in a tertiary care hospital in New Delhi, India.
Broor S, Gupta S, Mohapatra S, Kaushik S, Mir MA, Jain P, Dar L, Lal RB.
Source
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India. Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Abstract
Please cite this paper as: Broor et al. (2011) Emergence of 2009A/H1N1 cases in a tertiary care hospital in New Delhi, India. Influenza and Other Respiratory Viruses Doi: 10.1111/j.1750-2659.2011.00274.x. Objective To determine virologic and epidemiologic characteristics of pandemic (H1N1) 2009 at All India Institute of Medical Sciences (AIIMS) a tertiary care hospital in New Delhi, India. Methods Nasal and throat swabs from patients with febrile acute respiratory illness (FARI) from August to December 2009 (n = 1401) were tested for 2009A/H1N1 and seasonal influenza A viruses by real-time RT-PCR. Results Of 1401 samples tested, 475 (33?9%) were positive for influenza A, of these majority (412; 87%) were 2009A/H1N1, whereas the remaining 63 (13%) were seasonal influenza A (49 were A/H3 and 14 were A/H1). While co-circulation of 2009A/H1N1 and A/H3 was observed in August-September, subsequent months had exclusive pandemic influenza activity (October-December 2009). Pandemic 2009A/H1N1 emergence did not follow typical seasonal influenza seasonality in New Delhi, which normally peaks in July-August, but instead showed bimodal peaks in weeks 39 and 48 in 2009. The percent of specimens testing positive for 2009A/H1N1 influenza virus was found to be highest in >5- to 18-year age group (41?2%; OR = 2?3; CI = 1?6-3?2; P = 0?00). Conclusions Taken together, our data provide high prevalence of pandemic 2009A/H1N1 in urban New Delhi with bimodal peaks in weeks 39 and 48 and highest risk group being the children of school-going age (aged >5-18).
? 2011 Blackwell Publishing Ltd.
PMID:
21816007
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21816007
Emergence of 2009A/H1N1 cases in a tertiary care hospital in New Delhi, India.
Broor S, Gupta S, Mohapatra S, Kaushik S, Mir MA, Jain P, Dar L, Lal RB.
Source
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India. Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Abstract
Please cite this paper as: Broor et al. (2011) Emergence of 2009A/H1N1 cases in a tertiary care hospital in New Delhi, India. Influenza and Other Respiratory Viruses Doi: 10.1111/j.1750-2659.2011.00274.x. Objective To determine virologic and epidemiologic characteristics of pandemic (H1N1) 2009 at All India Institute of Medical Sciences (AIIMS) a tertiary care hospital in New Delhi, India. Methods Nasal and throat swabs from patients with febrile acute respiratory illness (FARI) from August to December 2009 (n = 1401) were tested for 2009A/H1N1 and seasonal influenza A viruses by real-time RT-PCR. Results Of 1401 samples tested, 475 (33?9%) were positive for influenza A, of these majority (412; 87%) were 2009A/H1N1, whereas the remaining 63 (13%) were seasonal influenza A (49 were A/H3 and 14 were A/H1). While co-circulation of 2009A/H1N1 and A/H3 was observed in August-September, subsequent months had exclusive pandemic influenza activity (October-December 2009). Pandemic 2009A/H1N1 emergence did not follow typical seasonal influenza seasonality in New Delhi, which normally peaks in July-August, but instead showed bimodal peaks in weeks 39 and 48 in 2009. The percent of specimens testing positive for 2009A/H1N1 influenza virus was found to be highest in >5- to 18-year age group (41?2%; OR = 2?3; CI = 1?6-3?2; P = 0?00). Conclusions Taken together, our data provide high prevalence of pandemic 2009A/H1N1 in urban New Delhi with bimodal peaks in weeks 39 and 48 and highest risk group being the children of school-going age (aged >5-18).
? 2011 Blackwell Publishing Ltd.
PMID:
21816007
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21816007