tetano
Editor, Senior Moderator
First published December 2011, doi: 10.1128/JVI.06824-11 JVI.06824-11
Emergence and dissemination of a swine H3N2 reassortant with 2009 pandemic H1N1 genes in pigs in China
Xiaohui Fan1,
Huachen Zhu2,3,
Boping Zhou2,
David K. Smith2,3,
Xinchun Chen2,
Tommy T.-Y. Lam3,
Leo L.M. Poon3,
Malik Peiris3 and
Yi Guan2,3,*
+ Author Affiliations
1Department of Microbiology, Guangxi Medical University, Nanning, China
2State Key Laboratory of Emerging Infectious Diseases (HKU-Shenzhen Branch), Shenzhen Third People's Hospital, Shenzhen, Guangdong, China
3State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
ABSTRACT
The 2009 pandemic influenza virus (pdm/09) has been frequently introduced to pigs and has reassorted with other swine viruses. Recently, H3N2 reassortants with pdm/09-like internal genes were isolated in Guangxi and Hong Kong. Genetic and epidemiological analyses suggest that these viruses have circulated in swine for some time. This is the first evidence that swine reassortant viruses with pdm/09-like genes may have become established in the field, altering the landscape of human and swine influenza.
http://jvi.asm.org/content/early/2011/12/07/JVI.06824-11.short
Emergence and dissemination of a swine H3N2 reassortant with 2009 pandemic H1N1 genes in pigs in China
Xiaohui Fan1,
Huachen Zhu2,3,
Boping Zhou2,
David K. Smith2,3,
Xinchun Chen2,
Tommy T.-Y. Lam3,
Leo L.M. Poon3,
Malik Peiris3 and
Yi Guan2,3,*
+ Author Affiliations
1Department of Microbiology, Guangxi Medical University, Nanning, China
2State Key Laboratory of Emerging Infectious Diseases (HKU-Shenzhen Branch), Shenzhen Third People's Hospital, Shenzhen, Guangdong, China
3State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
ABSTRACT
The 2009 pandemic influenza virus (pdm/09) has been frequently introduced to pigs and has reassorted with other swine viruses. Recently, H3N2 reassortants with pdm/09-like internal genes were isolated in Guangxi and Hong Kong. Genetic and epidemiological analyses suggest that these viruses have circulated in swine for some time. This is the first evidence that swine reassortant viruses with pdm/09-like genes may have become established in the field, altering the landscape of human and swine influenza.
http://jvi.asm.org/content/early/2011/12/07/JVI.06824-11.short