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Emergence and development of H7N9 influenza viruses in China

tetano

Editor, Senior Moderator
Curr Opin Virol. 2016 Feb 25;16:106-113. doi: 10.1016/j.coviro.2016.01.020. [Epub ahead of print]
[h=1]Emergence and development of H7N9 influenza viruses in China.[/h] Zhu H[SUP]1[/SUP], Lam TT[SUP]2[/SUP], Smith DK[SUP]2[/SUP], Guan Y[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] The occurrence of human infections with avian H7N9 viruses since 2013 demonstrates the continuing pandemic threat posed by the current influenza ecosystem in China. Influenza surveillance and phylogenetic analyses showed that these viruses were generated by multiple interspecies transmissions and reassortments among the viruses resident in domestic ducks and the H9N2 viruses enzootic in chickens. A large population of domestic ducks hosting diverse influenza viruses provided the precondition for these events to occur, while acquiring internal genes from enzootic H9N2 influenza viruses in chickens promoted the spread of these viruses. Human infections effectively act as sentinels, reflecting the intensity of the activity of these viruses in poultry.
Copyright ? 2016 Elsevier B.V. All rights reserved.


PMID: 26922715 [PubMed - as supplied by publisher]
 
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