tetano
Editor, Senior Moderator
Emerg Microbes Infect
. 2023 Sep 11;2258232.
doi: 10.1080/22221751.2023.2258232. Online ahead of print. Assessment of vaccinations and breakthrough infections after adjustment of the dynamic zero-COVID-19 strategy in China: An online survey
Shijie Qin[SUP] 1 2 [/SUP], Yanhua Li[SUP] 2 [/SUP], Likui Wang[SUP] 3 4 [/SUP], Xin Zhao[SUP] 2 [/SUP], Xiaopeng Ma[SUP] 1 [/SUP], George F Gao[SUP] 2 4 [/SUP]
Affiliations
Coronavirus disease 2019 (COVID-19) cases in China has grown rapidly after adjustment of the dynamic zero-COVID-19 strategy. However, how different vaccination states affect symptoms, severity and post COVID conditions was unclear. Here, we used an online questionnaire to investigate the infection status of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among 11897 participants, with 55.55% positive and 28.42% negative. The common COVID-19 symptoms were fatigue (73.31%), cough (70.02%), fever (65.25%) and overall soreness (58.64%); self-reported asymptomatic infection accounted for 0.7% of participants. The persistent symptoms at 1 month after infection included fatigue (48.7%), drowsiness (34.3%), cough (30.1%), decreased exercise ability (23.1%) and pharyngeal discomfort (19.4%), which was reduced by more than 200% at 2 months. Participants with complications such as chronic obstructive pulmonary disease, respiratory diseases, diabetes, hypertension, etc. have a higher proportion of hospitalization and longer recovery time (p<=0.01). Multiple vaccination statuses reduced the infection (p<0.001) and severity rates (p=0.022) by varying degrees as well as reduced the risk of high fever (> 39.1℃), chills, diarrhea and ageusia/anosmia, repectively (p<0.05). Vaccination may enhance some upper respiratory symptoms, including sore throat, nasal congestion and runny nose, repectively (p<0.05). Participants who had been vaccinated within 3 months were better protected by helping reduce their risk of overall soreness, chills and ageusia/anosmia, repectively (p<0.05). In conclusion, our work has updated the epidemic characteristics of the breakthrough infection (BTI) wave after the dynamic zero-COVID-19 strategy, providing data and insights on how different vaccination statuses affect COVID-19 symptoms and disease prognosis.
Keywords: Breakthrough infection; COVID-19; Omicron sub-variant; Post-COVID conditions; Vaccination.
. 2023 Sep 11;2258232.
doi: 10.1080/22221751.2023.2258232. Online ahead of print. Assessment of vaccinations and breakthrough infections after adjustment of the dynamic zero-COVID-19 strategy in China: An online survey
Shijie Qin[SUP] 1 2 [/SUP], Yanhua Li[SUP] 2 [/SUP], Likui Wang[SUP] 3 4 [/SUP], Xin Zhao[SUP] 2 [/SUP], Xiaopeng Ma[SUP] 1 [/SUP], George F Gao[SUP] 2 4 [/SUP]
Affiliations
- PMID: 37691586
- DOI: 10.1080/22221751.2023.2258232
Coronavirus disease 2019 (COVID-19) cases in China has grown rapidly after adjustment of the dynamic zero-COVID-19 strategy. However, how different vaccination states affect symptoms, severity and post COVID conditions was unclear. Here, we used an online questionnaire to investigate the infection status of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among 11897 participants, with 55.55% positive and 28.42% negative. The common COVID-19 symptoms were fatigue (73.31%), cough (70.02%), fever (65.25%) and overall soreness (58.64%); self-reported asymptomatic infection accounted for 0.7% of participants. The persistent symptoms at 1 month after infection included fatigue (48.7%), drowsiness (34.3%), cough (30.1%), decreased exercise ability (23.1%) and pharyngeal discomfort (19.4%), which was reduced by more than 200% at 2 months. Participants with complications such as chronic obstructive pulmonary disease, respiratory diseases, diabetes, hypertension, etc. have a higher proportion of hospitalization and longer recovery time (p<=0.01). Multiple vaccination statuses reduced the infection (p<0.001) and severity rates (p=0.022) by varying degrees as well as reduced the risk of high fever (> 39.1℃), chills, diarrhea and ageusia/anosmia, repectively (p<0.05). Vaccination may enhance some upper respiratory symptoms, including sore throat, nasal congestion and runny nose, repectively (p<0.05). Participants who had been vaccinated within 3 months were better protected by helping reduce their risk of overall soreness, chills and ageusia/anosmia, repectively (p<0.05). In conclusion, our work has updated the epidemic characteristics of the breakthrough infection (BTI) wave after the dynamic zero-COVID-19 strategy, providing data and insights on how different vaccination statuses affect COVID-19 symptoms and disease prognosis.
Keywords: Breakthrough infection; COVID-19; Omicron sub-variant; Post-COVID conditions; Vaccination.