tetano
Editor, Senior Moderator
Emerg Infect Dis
. 2024 Aug;30(8):1580-1588.
doi: 10.3201/eid3008.240225.
Wastewater Surveillance to Confirm Differences in Influenza A Infection between Michigan, USA, and Ontario, Canada, September 2022-March 2023
Ryland Corchis-Scott, Mackenzie Beach, Qiudi Geng, Ana Podadera, Owen Corchis-Scott, John Norton, Andrea Busch, Russell A Faust, Stacey McFarlane, Scott Withington, Bridget Irwin, Mehdi Aloosh, Kenneth K S Ng, R Michael McKay
Wastewater surveillance is an effective way to track the prevalence of infectious agents within a community and, potentially, the spread of pathogens between jurisdictions. We conducted a retrospective wastewater surveillance study of the 2022-23 influenza season in 2 communities, Detroit, Michigan, USA, and Windsor-Essex, Ontario, Canada, that form North America's largest cross-border conurbation. We observed a positive relationship between influenza-related hospitalizations and the influenza A virus (IAV) wastewater signal in Windsor-Essex (ρ = 0.785; p<0.001) and an association between influenza-related hospitalizations in Michigan and the IAV wastewater signal for Detroit (ρ = 0.769; p<0.001). Time-lagged cross correlation and qualitative examination of wastewater signal in the monitored sewersheds showed the peak of the IAV season in Detroit was delayed behind Windsor-Essex by 3 weeks. Wastewater surveillance for IAV reflects regional differences in infection dynamics which may be influenced by many factors, including the timing of vaccine administration between jurisdictions.
Keywords: Canada; Michigan; Ontario; United States; epidemiology; influenza; influenza A virus; prevalence; respiratory infections; vaccination; viruses; wastewater surveillance.
. 2024 Aug;30(8):1580-1588.
doi: 10.3201/eid3008.240225.
Wastewater Surveillance to Confirm Differences in Influenza A Infection between Michigan, USA, and Ontario, Canada, September 2022-March 2023
Ryland Corchis-Scott, Mackenzie Beach, Qiudi Geng, Ana Podadera, Owen Corchis-Scott, John Norton, Andrea Busch, Russell A Faust, Stacey McFarlane, Scott Withington, Bridget Irwin, Mehdi Aloosh, Kenneth K S Ng, R Michael McKay
- PMID: 39043398
- DOI: 10.3201/eid3008.240225
Wastewater surveillance is an effective way to track the prevalence of infectious agents within a community and, potentially, the spread of pathogens between jurisdictions. We conducted a retrospective wastewater surveillance study of the 2022-23 influenza season in 2 communities, Detroit, Michigan, USA, and Windsor-Essex, Ontario, Canada, that form North America's largest cross-border conurbation. We observed a positive relationship between influenza-related hospitalizations and the influenza A virus (IAV) wastewater signal in Windsor-Essex (ρ = 0.785; p<0.001) and an association between influenza-related hospitalizations in Michigan and the IAV wastewater signal for Detroit (ρ = 0.769; p<0.001). Time-lagged cross correlation and qualitative examination of wastewater signal in the monitored sewersheds showed the peak of the IAV season in Detroit was delayed behind Windsor-Essex by 3 weeks. Wastewater surveillance for IAV reflects regional differences in infection dynamics which may be influenced by many factors, including the timing of vaccine administration between jurisdictions.
Keywords: Canada; Michigan; Ontario; United States; epidemiology; influenza; influenza A virus; prevalence; respiratory infections; vaccination; viruses; wastewater surveillance.